Publications

from 2001 to present

2018

A. Benjak; C. Avanzi; P. Singh; C. Loiseau; S. Girma et al. : Phylogenomics and antimicrobial resistance of the leprosy bacillus Mycobacterium leprae; Nature Communications. 2018. DOI : 10.1038/s41467-017-02576-z.
F. Glaus; D. Dedic; P. Tare; V. Nagaraja; L. Rodrigues et al. : Total Synthesis of Ripostatin B and Structure-Activity Relationship Studies on Ripostatin Analogs; J. Org. Chem.. 2018. DOI : 10.1021/acs.joc.8b00193.
F. Boldrin; G. Degiacomi; A. Serafini; G. Kolly; M. Ventura et al. : Promoter mutagenesis for fine-tuning expression of essential genes in Mycobacterium tuberculosis; Microb. Biotechnol.. 2018. DOI : 10.1111/1751-7915.12875.
M. da Silva; J. Portela; W. Li; M. Jackson; M. Gonzalez-Juarrero et al. : Evidence of zoonotic leprosy in Para A, Brazilian Amazon, and risks associated with human contact or consumption of armadillos; Plos Neglect. Trop. Dis.. 2018. DOI : 10.1371/journal.pntd.0006532.
V. Schuenemann; C. Avanzi; B. Krause-Kyora; A. Seitz; A. Herbig et al. : Ancient Mycobacterium leprae genomes reveal an unexpected diversity of leprosy in medieval Europe.
V. Schuenemann; C. Avanzi; B. Krause-Kyora; A. Seitz; A. Herbig et al. : Ancient genomes reveal a high diversity of Mycobacterium leprae in medieval Europe; PLoS Pathog.. 2018. DOI : 10.1371/journal.ppat.1006997.
L. Chiarelli; G. Mori; B. Orena; M. Esposito; T. Lane et al. : A multitarget approach to drug discovery inhibiting Mycobacterium tuberculosis PyrG and PanK; Sci Rep. 2018. DOI : 10.1038/s41598-018-21614-4.
S.-Y. C. Foo : More Medicines for Tuberculosis: Fuelling Drug Discovery against Mycobacterium tuberculosis. Lausanne, EPFL, 2018. DOI : 10.5075/epfl-thesis-8906.
C. Avanzi : Genomics: a Swiss army knife to fight leprosy. Lausanne, EPFL, 2018. DOI : 10.5075/epfl-thesis-8482.
F. Boldrin; G. Degiacomi; A. Serafini; G. S. Kolly; M. Ventura et al. : Promoter mutagenesis for fine-tuning expression of essential genes in Mycobacterium tuberculosis; Microbial Biotechnology. 2018. DOI : 10.1111/1751-7915.12875.

2017

A. Benjak; T. P. Honap; C. Avanzi; E. Becerril-Villanueva; I. Estrada-Garcia et al. : Insights from the Genome Sequence of Mycobacterium lepraemurium: Massive Gene Decay and Reductive Evolution; Mbio. 2017. DOI : 10.1128/mBio.01283-17.
A.-S. Foscolos; I. Papanastasiou; A. Tsotinis; N. Kolocouris; G. B. Foscolos et al. : Synthesis of Adamantane Aminoethers with Antitubercular Potential; Medicinal Chemistry. 2017. DOI : 10.2174/1573406413666170125112709.
N. T. Odermatt : Functional Characterization of Nucleoid Associated Proteins Acting as Global Transcription Factors in Mycobacterium tuberculosis. Lausanne, EPFL, 2017. DOI : 10.5075/epfl-thesis-8176.
E. G. Salina; O. Ryabova; A. Vocat; B. Nikonenko; S. T. Cole et al. : New 1-hydroxy-2-thiopyridine derivatives active against both replicating and dormant Mycobacterium tuberculosis; Journal Of Infection And Chemotherapy. 2017. DOI : 10.1016/j.jiac.2017.04.012.
N. T. Odermatt; C. Sala; A. Benjak; G. S. Kolly; A. Vocat et al. : Rv3852 (H-NS) of Mycobacterium tuberculosis Is Not Involved in Nucleoid Compaction and Virulence Regulation; Journal Of Bacteriology. 2017. DOI : 10.1128/Jb.00129-17.
M. Gengenbacher; M. A. Duque-Correa; P. Kaiser; S. Schuerer; D. Lazar et al. : NOS2-deficient mice with hypoxic necrotizing lung lesions predict outcomes of tuberculosis chemotherapy in humans; Scientific Reports. 2017. DOI : 10.1038/s41598-017-09177-2.
M. M. A. Stefani; C. Avanzi; S. Buhrer-Sekula; A. Benjak; C. Loiseau et al. : Whole genome sequencing distinguishes between relapse and reinfection in recurrent leprosy cases; Plos Neglected Tropical Diseases. 2017. DOI : 10.1371/journal.pntd.0005598.
M. Vlachou; A. Siamidi; E. Diamantidi; A. Iliopoulou; I. Papanastasiou et al. : In vitro Controlled Release from Solid Pharmaceutical Formulations of two new Adamantane Aminoethers with Antitubercular Activity (I).; Drug Research. 2017. DOI : 10.1055/s-0042-121491.
W. Ahmed; C. Sala; S. R. Hegde; R. K. Jha; S. T. Cole et al. : Transcription facilitated genome-wide recruitment of topoisomerase I and DNA gyrase; Plos Genetics. 2017. DOI : 10.1371/journal.pgen.1006754.
L. Song; M. Jenner; J. Masschelein; C. Jones; M. J. Bull et al. : Discovery and Biosynthesis of Gladiolin: A Burkholderia gladioli Antibiotic with Promising Activity against Mycobacterium tuberculosis; Journal Of The American Chemical Society. 2017. DOI : 10.1021/jacs.7b03382.
M. Leroy; J. Piton; L. Gilet; O. Pellegrini; C. Proux et al. : Rae1/YacP, a new endoribonuclease involved in ribosome-dependent mRNA decay in Bacillus subtilis; Embo Journal. 2017. DOI : 10.15252/embj.201796540.
J. Piton; C. S. -Y. Foo; S. T. Cole : Structural studies of Mycobacterium tuberculosis DprE1 interacting with its inhabitors; Drug Discovery Today. 2017. DOI : 10.1016/j.drudis.2016.09.014.
S. T. Cole : Tuberculosis drug discovery needs public-private consortia; Drug Discovery Today. 2017. DOI : 10.1016/j.drudis.2016.09.026.
Y. Lou; J. Rybniker; C. Sala; S. T. Cole : EspC forms a filamentous structure in the cell envelope of Mycobacterium tuberculosis and impacts ESX-1 secretion; Molecular Microbiology. 2017. DOI : 10.1111/mmi.13575.
V. Singh; N. Dhar; J. Pato; G. S. Kolly; J. Kordulakova et al. : Identification of aminopyrimidine-sulfonamides as potent modulators of Wag31-mediated cell elongation in mycobacteria; Molecular Microbiology. 2017. DOI : 10.1111/mmi.13535.
G. Degiacomi; A. Benjak; J. Madacki; F. Boldrin; R. Provvedi et al. : Essentiality of mmpL3 and impact of its silencing on Mycobacterium tuberculosis gene expression; Scientific Reports. 2017. DOI : 10.1038/srep43495.
V. Singh; S. Donini; A. Pacitto; C. Sala; R. C. Hartkoorn et al. : The Inosine Monophosphate Dehydrogenase, GuaB2, Is a Vulnerable New Bactericidal Drug Target for Tuberculosis; Acs Infectious Diseases. 2017. DOI : 10.1021/acsinfecdis.6b00102.

2016

S. Cole; J. L. Rybniker ; Benzimidazole sulfide derivatives for the treatment or prevention of tuberculosis. EP3250205 ; WO2016120259 ; EP3050565 . 2016.
J. Rybniker; S. Cole; G. Keri; L. Orfi; J. Pato et al. ; Benzothiophene, benzyloxybenzylidene and indoline derivatives useful for the treatment of tuberculosis. US2017240522 ; EP3194366 ; WO2016041972 . 2016.
C. Stewart; M. V. Albertovich ; 2-homopiperazine-1-yl-4h-1,3-benzothiazine-4-one derivatives and process for the preparation of 2- (homo)piperazine 1,3-benzothiazine-4-one hydrochlorides. WO2016151011 ; CA2980653 ; EP3072889 . 2016.
C. S.-Y. Foo; B. Lechartier; G. S. Kolly; S. Boy-Rottger; J. Neres et al. : Characterization of DprE1-Mediated Benzothiazinone Resistance in Mycobacterium tuberculosis; Antimicrobial Agents And Chemotherapy. 2016. DOI : 10.1128/Aac.01523-16.
A. Benard; C. Sala; G. Pluschke : Mycobacterium ulcerans Mouse Model Refinement for Pre-Clinical Profiling of Vaccine Candidates; Plos One. 2016. DOI : 10.1371/journal.pone.0167059.
S. T. Cole : Inhibiting Mycobacterium tuberculosis within and without; Philosophical Transactions Of The Royal Society B-Biological Sciences. 2016. DOI : 10.1098/rstb.2015.0506.
C. Avanzi; J. Del-Pozo; A. Benjak; K. Stevenson; V. R. Simpson et al. : Red squirrels in the British Isles are infected with leprosy bacilli; Science. 2016. DOI : 10.1126/science.aah3783.
C. Avanzi; P. Busso; A. Benjak; C. Loiseau; A. Fomba et al. : Transmission of drug-resistant leprosy in Guinea-Conakry detected by molecular epidemiological approaches; Clinical Infectious Disease. 2016. DOI : 10.1093/cid/ciw572.
G. Degiacomi; Y. Personne; G. Mondesert; X. Ge; C. S. Mandava et al. : Micrococcin P1-A bactericidal thiopeptide active against Mycobacterium tuberculosis; Tuberculosis. 2016. DOI : 10.1016/j.tube.2016.07.011.
Y. Lou : Structural and functional characterization of the mycobacterial ESX-1 secretion system. Lausanne, EPFL, 2016. DOI : 10.5075/epfl-thesis-7093.
G. Karabanovich; J. Zemanova; T. Smutny; R. Szekely; M. Sarkan et al. : Development of 3,5-Dinitrobenzylsulfanyl-1,3,4-oxadiazoles and Thiadiazoles as Selective Antitubercular Agents Active Against Replicating and Nonreplicating Mycobacterium tuberculosis; Journal Of Medicinal Chemistry. 2016. DOI : 10.1021/acs.jmedchem.5b00608.
R. Szekely; S. T. Cole : Mechanistic insight into mycobacterial MmpL protein function; Molecular Microbiology. 2016. DOI : 10.1111/mmi.13306.
A. Benjak; S. Uplekar; M. Zhang; J. Piton; S. T. Cole et al. : Genomic and transcriptomic analysis of the streptomycin-dependent Mycobacterium tuberculosis strain 18b; Bmc Genomics. 2016. DOI : 10.1186/s12864-016-2528-2.

2015

Z. Greff; Z. Varga; G. Kéri; L. Õrfi; J. Pató et al. ; 4-Pyrimidinylamino-benzenesulfonamide derivatives and their use for the inhibition of polo-like kinase 1 (PLK1) for the treatment of cancer and their use for the treatment of bacterial infections. US2015368209 ; EP2941428 ; WO2014106762 . 2015.
N. Alejandra Gonzalez-Martinez; H. Gerardo Lozano-Garza; J. Castro-Garza; A. De Osio-Cortez; J. Vargas-Villarreal et al. : In Vivo Activity of the Benzothiazinones PBTZ169 and BTZ043 against Nocardia brasiliensis; PLoS Neglected Tropical Diseases. 2015. DOI : 10.1371/journal.pntd.0004022.
R. Sharma; P. Singh; W. J. Loughry; J. M. Lockhart; W. B. Inman et al. : Zoonotic Leprosy in the Southeastern United States; Emerging Infectious Diseases. 2015. DOI : 10.3201/eid2112.150501.
S. Landge; A. B. Mullick; K. Nagalapur; J. Neres; V. Subbulakshmi et al. : Discovery of benzothiazoles as antimycobacterial agents: Synthesis, structure-activity relationships and binding studies with Mycobacterium tuberculosis decaprenylphosphoryl-beta-D-ribose 2 '-oxidase; Bioorganic & Medicinal Chemistry. 2015. DOI : 10.1016/j.bmc.2015.11.017.
J. -Y. Gillon; B. Lechartier; V. A. Makarov; S. T. Cole : Towards first in human clinical trial with the novel drug candidate PBTZ169. 2015. p. 24-24.
M. Petridis; A. Benjak; G. M. Cook : Defining the nitrogen regulated transcriptome of Mycobacterium smegmatis using continuous culture; Bmc Genomics. 2015. DOI : 10.1186/s12864-015-2051-x.
G. S. Kolly; R. Mukherjee; E. Kilacskova; L. A. Abriata; M. Raccaud et al. : GtrA Protein Rv3789 Is Required for Arabinosylation of Arabinogalactan in Mycobacterium tuberculosis; Journal Of Bacteriology. 2015. DOI : 10.1128/Jb.00628-15.
A. Vocat; R. C. Hartkoorn; B. Lechartier; M. Zhang; N. Dhar et al. : Bioluminescence for Assessing Drug Potency against Nonreplicating Mycobacterium tuberculosis; Antimicrobial Agents And Chemotherapy. 2015. DOI : 10.1128/Aac.00528-15.
B. Lechartier; S. T. Cole : Mode of Action of Clofazimine and Combination Therapy with Benzothiazinones against Mycobacterium tuberculosis; Antimicrobial Agents And Chemotherapy. 2015. DOI : 10.1128/Aac.00395-15.
V. Makarov; J. Neres; R. C. Hartkoorn; O. B. Ryabova; E. Kazakova et al. : The 8-Pyrrole-Benzothiazinones Are Noncovalent Inhibitors of DprE1 from Mycobacterium tuberculosis; Antimicrobial Agents And Chemotherapy. 2015. DOI : 10.1128/Aac.00778-15.
A. Sipos; J. Pato; R. Szekely; R. C. Hartkoorn; L. Kekesi et al. : Lead selection and characterization of antitubercular compounds using the Nested Chemical Library; Tuberculosis. 2015. DOI : 10.1016/j.tube.2015.02.028.
L. Vera-Cabrera; W. Escalante-Fuentes; S. S. Ocampo-Garza; J. Ocampo-Candiani; C. A. Molina-Torres et al. : Mycobacterium lepromatosis Infections in Nuevo Leon, Mexico; Journal Of Clinical Microbiology. 2015. DOI : 10.1128/Jcm.03667-14.
R. Wassermann; M. F. Gulen; C. Sala; S. G. Perin; Y. Lou et al. : Mycobacterium tuberculosis Differentially Activates cGAS- and Inflammasome-Dependent Intracellular Immune Responses through ESX-1; Cell Host & Microbe. 2015. DOI : 10.1016/j.chom.2015.05.003.
M. Brecik; I. Centarova; R. Mukherjee; G. S. Kolly; S. Huszar et al. : DprE1 Is a Vulnerable Tuberculosis Drug Target Due to Its Cell Wall Localization; Acs Chemical Biology. 2015. DOI : 10.1021/acschembio.5b00237.
J. Rybniker; A. Vocat; C. Sala; P. Busso; F. Pojer et al. : Lansoprazole is an antituberculous prodrug targeting cytochrome bc1; Nature Communications. 2015. DOI : 10.1038/ncomms8659.
G. Mori; L. R. Chiarelli; M. Esposito; V. Makarov; M. Bellinzoni et al. : Thiophenecarboxamide Derivatives Activated by EthA Kill Mycobacterium tuberculosis by Inhibiting the CTP Synthetase PyrG; Chemistry & Biology. 2015. DOI : 10.1016/j.chembiol.2015.05.016.
N. Korotkova; J. Piton; J. M. Wagner; S. Boy-Roettger; A. Japaridze et al. : Structure of EspB, a secreted substrate of the ESX-1 secretion system of Mycobacterium tuberculosis; Journal Of Structural Biology. 2015. DOI : 10.1016/j.jsb.2015.06.003.
S. J. Tantry; G. Degiacomi; S. Sharma; L. K. Jena; A. Narayan et al. : Whole cell screen based identification of spiropiperidines with potent antitubercular properties; Bioorganic & Medicinal Chemistry Letters. 2015. DOI : 10.1016/j.bmcl.2015.05.087.
J. Neres; R. C. Hartkoorn; L. R. Chiarelli; R. Gadupudi; M. R. Pasca et al. : 2-Carboxyquinoxalines Kill Mycobacterium tuberculosis through Noncovalent Inhibition of DprE1; Acs Chemical Biology. 2015. DOI : 10.1021/cb5007163.
P. Singh; A. Benjak; V. J. Schuenemann; A. Herbig; C. Avanzi et al. : Insight into the evolution and origin of leprosy bacilli from the genome sequence of Mycobacterium lepromatosis; Proceedings Of The National Academy Of Sciences Of The United States Of America. 2015. DOI : 10.1073/pnas.1421504112.

2014

P. D. Townsend; B. Jungwirth; F. Pojer; M. Bussmann; V. A. Money et al. : The Crystal Structures of Apo and cAMP-Bound GlxR from Corynebacterium glutamicum Reveal Structural and Dynamic Changes upon cAMP Binding in CRP/FNR Family Transcription Factors; Plos One. 2014. DOI : 10.1371/journal.pone.0113265.
P. Singh; A. Benjak; S. Carat; M. Kai; P. Busso et al. : Genome-wide re-sequencing of multidrug-resistant Mycobacterium leprae Airaku-3; Clinical Microbiology And Infection. 2014. DOI : 10.1111/1469-0691.12609.
J. Rybniker; J. M. Chen; C. Sala; R. C. Hartkoorn; A. Vocat et al. : Anticytolytic Screen Identifies Inhibitors of Mycobacterial Virulence Protein Secretion; Cell Host & Microbe. 2014. DOI : 10.1016/j.chom.2014.09.008.
M. Bellinzoni; A. Haouz; I. Miras; S. Magnet; G. Andre-Leroux et al. : Structural studies suggest a peptidoglycan hydrolase function for the Mycobacterium tuberculosis Tat-secreted protein Rv2525c; Journal Of Structural Biology. 2014. DOI : 10.1016/j.jsb.2014.09.003.
F. Boldrin; M. Ventura; G. Degiacomi; S. Ravishankar; C. Sala et al. : The Phosphatidyl-myo-Inositol Mannosyltransferase PimA Is Essential for Mycobacterium tuberculosis Growth In Vitro and In Vivo (vol 196, pg 3441, 2014); Journal Of Bacteriology. 2014. DOI : 10.1128/Jb.02332-14.
G. S. Kolly : Genetic analysis of the decaprenyl-phospho-D-arabinofuranose pathway in Mycobacterium tuberculosis. Lausanne, EPFL, 2014. DOI : 10.5075/epfl-thesis-6352.
M. Zhang; J. M. Chen; C. Sala; J. Rybniker; N. Dhar et al. : EspI regulates the ESX-1 secretion system in response to ATP levels in Mycobacterium tuberculosis; Molecular Microbiology. 2014. DOI : 10.1111/mmi.12718.
G. S. Kolly; C. Sala; A. Vocat; S. T. Cole : Assessing essentiality of transketolase in Mycobacterium tuberculosis using an inducible protein degradation system; Fems Microbiology Letters. 2014. DOI : 10.1111/1574-6968.12536.
F. Boldrin; M. Ventura; G. Degiacomi; S. Ravishankar; C. Sala et al. : The Phosphatidyl-myo-Inositol Mannosyltransferase PimA Is Essential for Mycobacterium tuberculosis Growth In Vitro and In Vivo; Journal Of Bacteriology. 2014. DOI : 10.1128/Jb.01346-13.
L. Solans; J. Gonzalo-Asensio; C. Sala; A. Benjak; S. Uplekar et al. : The PhoP-Dependent ncRNA Mcr7 Modulates the TAT Secretion System in Mycobacterium tuberculosis; Plos Pathogens. 2014. DOI : 10.1371/journal.ppat.1004183.
M. Zhang; C. Sala; N. Dhar; A. Vocat; V. K. Sambandamurthy et al. : In Vitro and In Vivo Activities of Three Oxazolidinones against Nonreplicating Mycobacterium tuberculosis; Antimicrobial Agents And Chemotherapy. 2014. DOI : 10.1128/Aac.02410-14.
D. Albesa-Jove; L. R. Chiarelli; V. Makarov; M. R. Pasca; S. Urresti et al. : Rv2466c Mediates the Activation of TP053 To Kill Replicating and Non-replicating Mycobacterium tuberculosis; Acs Chemical Biology. 2014. DOI : 10.1021/cb500149m.
K. Mikusova; V. Makarov; J. Neres : DprE1-from the Discovery to the Promising Tuberculosis Drug Target; Current Pharmaceutical Design. 2014.
B. Lechartier : Benzothiazinones: from a new lead to new combination therapies against Mycobacterium tuberculosis. Lausanne, EPFL, 2014. DOI : 10.5075/epfl-thesis-6239.
J. Rybniker; F. Pojer; J. Marienhagen; G. S. Kolly; J. M. Chen et al. : The cysteine desulfurase IscS of Mycobacterium tuberculosis is involved in iron sulfur cluster biogenesis and oxidative stress defence; Biochemical Journal. 2014. DOI : 10.1042/Bj20130732.
S. T. Cole : Who will develop new antibacterial agents?; Philosophical Transactions Of The Royal Society B-Biological Sciences. 2014. DOI : 10.1098/rstb.2013.0430.
G. S. Kolly; F. Boldrin; C. Sala; N. Dhar; R. C. Hartkoorn et al. : Assessing the essentiality of the decaprenyl-phospho-D-arabinofuranose pathway in Mycobacterium tuberculosis using conditional mutants; Molecular Microbiology. 2014. DOI : 10.1111/mmi.12546.
T. A. Mendum; V. J. Schuenemann; S. Roffey; G. M. Taylor; H. Wu et al. : Mycobacterium leprae genomes from a British medieval leprosy hospital: towards understanding an ancient epidemic; Bmc Genomics. 2014. DOI : 10.1186/1471-2164-15-270.
R. C. Hartkoorn; S. Uplekar; S. T. Cole : Cross-Resistance between Clofazimine and Bedaquiline through Upregulation of MmpL5 in Mycobacterium tuberculosis; Antimicrobial Agents And Chemotherapy. 2014. DOI : 10.1128/Aac.00037-14.
R. C. Hartkoorn; O. B. Ryabova; L. R. Chiarelli; G. Riccardi; V. Makarov et al. : Mechanism of Action of 5-Nitrothiophenes against Mycobacterium tuberculosis; Antimicrobial Agents And Chemotherapy. 2014. DOI : 10.1128/Aac.02693-13.
K. Li; L. A. Schurig-Briccio; X. Feng; A. Upadhyay; V. Pujari et al. : Multitarget Drug Discovery for Tuberculosis and Other Infectious Diseases; Journal Of Medicinal Chemistry. 2014. DOI : 10.1021/jm500131s.
S. Surade; N. Ty; N. Hengrung; B. Lechartier; S. T. Cole et al. : A structure-guided fragment-based approach for the discovery of allosteric inhibitors targeting the lipophilic binding site of transcription factor EthR; Biochemical Journal. 2014. DOI : 10.1042/Bj20131127.
A. I. Zumla; S. H. Gillespie; M. Hoelscher; P. P. J. Philips; S. T. Cole et al. : New antituberculosis drugs, regimens, and adjunct therapies: needs, advances, and future prospects; Lancet Infectious Diseases. 2014. DOI : 10.1016/S1473-3099(13)70328-1.
V. Makarov; B. Lechartier; M. Zhang; J. de Almeida Neres; J. Pedro et al. : Towards a new combination therapy for tuberculosis with next generation benzothiazinones; Embo Molecular Medicine. 2014. DOI : 10.1002/emmm.201303575.
D. E. Minnikin; G. M. Taylor; G. R. Stewart; T. A. Mendum; S. Roffey et al. : Defining the origins and spread of leprosy using molecular biomarkers. 2014. 83rd Annual Meeting of the American-Association-of-Physical-Anthropologists. p. 186-187.
R. C. Hartkoorn; F. Pojer; J. A. Read; H. Gingell; J. Neres et al. : Pyridomycin bridges the NADH- and substratebinding pockets of the enoyl reductase InhA; Nature Chemical Biology. 2014.
B. Lechartier; J. Rybniker; A. Zumla; S. T. Cole : Tuberculosis drug discovery in the post-post-genomic era; Embo Molecular Medicine. 2014. DOI : 10.1002/emmm.201201772.
C. S. Smith; S. K. Noordeen; J. H. Richardus; H. Sansarricq; S. T. Cole et al. : A strategy to halt leprosy transmission; Lancet Infectious Diseases. 2014.
B. Blasco : Structure-function analysis of the EspR virulence regulator of Mycobacterium tuberculosis. Lausanne, EPFL, 2014. DOI : 10.5075/epfl-thesis-6000.

2013

V. Makarov; S. Cole : New Generation Benzothiazinones For Tuberculosis Therapy. 2013. p. 79-79.
J. M. Chen; M. Zhang; J. Rybniker; L. Basterra; N. Dhar et al. : Phenotypic Profiling of Mycobacterium tuberculosis EspA Point Mutants Reveals that Blockage of ESAT-6 and CFP-10 Secretion In Vitro Does Not Always Correlate with Attenuation of Virulence; Journal Of Bacteriology. 2013. DOI : 10.1128/Jb.00967-13.
J. M. Chen; M. Zhang; J. Rybniker; S. Boy-Röttger; N. Dhar et al. : Mycobacterium tuberculosis EspB binds phospholipids and mediates EsxA-independent virulence; Molecular Microbiology. 2013. DOI : 10.1111/mmi.12336.
G. M. Taylor; K. Tucker; R. Butler; A. W. G. Pike; J. Lewis et al. : Detection and Strain Typing of Ancient Mycobacterium leprae from a Medieval Leprosy Hospital; Plos One. 2013. DOI : 10.1371/journal.pone.0062406.
A. Zumla; P. Nahid; S. T. Cole : Advances in the development of new tuberculosis drugs and treatment regimens; Nature Reviews Drug Discovery. 2013. DOI : 10.1038/nrd4001.
J. Vanhomwegen; N. Berthet; C. Mazuet; G. Guigon; T. Vallaeys et al. : Application of High-Density DNA Resequencing Microarray for Detection and Characterization of Botulinum Neurotoxin-Producing Clostridia; Plos One. 2013. DOI : 10.1371/journal.pone.0067510.
V. J. Schuenemann; P. Singh; T. A. Mendum; B. Krause-Kyora; G. Jäger et al. : Genome-wide comparison of medieval and modern Mycobacterium leprae; Science (New York, N.Y.). 2013. DOI : 10.1126/science.1238286.
M. Zhang : Novel strategies for the development of anti-tuberculosis compounds. Lausanne, EPFL, 2013. DOI : 10.5075/epfl-thesis-5838.
H. Haruki; M. G. Pedersen; K. I. Gorska; F. Pojer; K. Johnsson : Tetrahydrobiopterin Biosynthesis as an Off-Target of Sulfa Drugs; Science. 2013. DOI : 10.1126/science.1232972.
I. Abubakar; M. Zignol; D. Falzon; M. Raviglione; L. Ditiu et al. : Drug-resistant tuberculosis: time for visionary political leadership; The Lancet Infectious Diseases. 2013. DOI : 10.1016/S1473-3099(13)70030-6.
R. S. Wallis; P. Kim; S. Cole; D. Hanna; B. B. Andrade et al. : Tuberculosis biomarkers discovery: developments, needs, and challenges; The Lancet infectious diseases. 2013. DOI : 10.1016/S1473-3099(13)70034-3.
S. Uplekar; J. Rougemont; S. T. Cole; C. Sala : High-resolution transcriptome and genome-wide dynamics of RNA polymerase and NusA in Mycobacterium tuberculosis; Nucleic Acids Research. 2013. DOI : 10.1093/nar/gks1260.
R. A. Slayden; M. Jackson; J. Zucker; M. V. Ramirez; C. C. Dawson et al. : Updating and curating metabolic pathways of TB; Tuberculosis. 2013. DOI : 10.1016/j.tube.2012.11.001.
J. M. Lew; C. Mao; M. Shukla; A. Warren; R. Will et al. : Database resources for the tuberculosis community; Tuberculosis. 2013. DOI : 10.1016/j.tube.2012.11.003.
B. Jungwirth; C. Sala; T. A. Kohl; S. Uplekar; J. Baumbach et al. : High-resolution detection of DNA binding sites of the global transcriptional regulator GlxR in Corynebacterium glutamicum; Microbiology-Sgm. 2013. DOI : 10.1099/mic.0.062059-0.
O. P. Horlacher; R. C. Hartkoorn; S. T. Cole; K.-H. Altmann : Synthesis and Antimycobacterial Activity of 2,1 '-Dihydropyridomycins; Acs Medicinal Chemistry Letters. 2013. DOI : 10.1021/ml300385q.

2012

V. Makarov; S. Cole ; 2-piperazin-1-yl-4h-1,3-benzothiazin-4-one derivatives and their use for the treatment of mammalian infections. CA2817931 ; CN107011287 ; AU2011330742 ; GEP201606545 ; IL226289 ; US8796264 ; KR20140012956 ; ZA201303829 ; EP2640712 ; US2013245007 ; CN103221399 ; AU2011330742 ; CA2817931 ; WO2012066518 ; EA023879 . 2012.
J. M. Chen; S. Uplekar; S. V. Gordon; S. T. Cole : A Point Mutation in cycA Partially Contributes to the D-cycloserine Resistance Trait of Mycobacterium bovis BCG Vaccine Strains; Plos One. 2012. DOI : 10.1371/journal.pone.0043467.
J. Neres; F. Pojer; E. Molteni; L. R. Chiarelli; N. Dhar et al. : Structural Basis for Benzothiazinone-Mediated Killing of Mycobacterium tuberculosis; Science Translational Medicine. 2012. DOI : 10.1126/scitranslmed.3004395.
R. C. Hartkoorn; C. Sala; J. Neres; F. Pojer; S. Magnet et al. : Towards a new tuberculosis drug: pyridomycin - nature's isoniazid; Embo Molecular Medicine. 2012. DOI : 10.1002/emmm.201201689.
B. Lechartier; R. C. Hartkoorn; S. T. Cole : In Vitro Combination Studies of Benzothiazinone Lead Compound BTZ043 against Mycobacterium tuberculosis; Antimicrobial Agents And Chemotherapy. 2012. DOI : 10.1128/Aac.01476-12.
M. Zhang; C. Sala; R. C. Hartkoorn; N. Dhar; A. Mendoza-Losana et al. : Streptomycin-Starved Mycobacterium tuberculosis 18b, a Drug Discovery Tool for Latent Tuberculosis; Antimicrobial Agents And Chemotherapy. 2012. DOI : 10.1128/Aac.01125-12.
B. D. Robertson; D. Altmann; C. Barry; B. Bishai; S. Cole et al. : Detection and treatment of subclinical tuberculosis; Tuberculosis. 2012. DOI : 10.1016/j.tube.2012.06.004.
S. Uplekar : Genomics and transcriptomics of the Mycobacterium tuberculosis complex. Lausanne, EPFL, 2012. DOI : 10.5075/epfl-thesis-5550.
L. Vera-Cabrera; M. P. Campos-Rivera; N. A. Gonzalez-Martinez; J. Ocampo-Candiani; S. T. Cole : In Vitro Activities of the New Antitubercular Agents PA-824 and BTZ043 against Nocardia brasiliensis; Antimicrobial Agents And Chemotherapy. 2012. DOI : 10.1128/AAC.00115-12.
M. Raviglione; B. Marais; K. Floyd; K. Loennroth; H. Getahun et al. : Scaling up interventions to achieve global tuberculosis control: progress and new developments; Lancet. 2012.
B. Blasco; J. M. Chen; R. Hartkoorn; C. Sala; S. Uplekar et al. : Virulence Regulator EspR of Mycobacterium tuberculosis Is a Nucleoid-Associated Protein; Plos Pathogens. 2012. DOI : 10.1371/journal.ppat.1002621.
R. C. Hartkoorn; C. Sala; S. Uplekar; P. Busso; J. Rougemont et al. : Genome-Wide Definition of the SigF Regulon in Mycobacterium tuberculosis; Journal Of Bacteriology. 2012. DOI : 10.1128/JB.06692-11.
S. T. Cole : INFECTIOUS DISEASES Transporter targeted in tuberculosis; Nature Chemical Biology. 2012. DOI : 10.1038/nchembio.918.
B. Mollwitz; E. Brunk; S. Schmitt; F. Pojer; M. Bannwarth et al. : Directed evolution of the suicide protein O⁶-alkylguanine-DNA alkyltransferase for increased reactivity results in an alkylated protein with exceptional stability; Biochemistry. 2012. DOI : 10.1021/bi2016537.
E. Fullam; F. Pojer; T. Bergfors; T. A. Jones; S. T. Cole : Structure and function of the transketolase from Mycobacterium tuberculosis and comparison with the human enzyme; Open Biology. 2012. DOI : 10.1098/rsob.110026.
C. Trefzer; H. Škovierová; S. Buroni; A. Bobovská; S. Nenci et al. : Benzothiazinones Are Suicide Inhibitors of Mycobacterial Decaprenylphosphoryl-β-; Journal of the American Chemical Society. 2012. DOI : 10.1021/ja211042r.

2011

C. Sala; R. C. Hartkoorn : Tuberculosis drugs: new candidates and how to find more; Future microbiology. 2011. DOI : 10.2217/fmb.11.46.
J. M. Chen; S. Boy-Röttger; N. Dhar; N. Sweeney; R. S. Buxton et al. : EspD Is Critical for the Virulence-Mediating ESX-1 Secretion System in Mycobacterium tuberculosis; Journal of bacteriology. 2011. DOI : 10.1128/JB.06417-11.
M. Zhang; S.-Y. Li; I. M. Rosenthal; D. V. Almeida; Z. Ahmad et al. : Treatment of Tuberculosis with Rifamycin-containing Regimens in Immune-deficient Mice; American Journal Of Respiratory And Critical Care Medicine. 2011. DOI : 10.1164/rccm.201012-1949OC.
S. Cole : New medicines for tuberculosis: benzothiazinones. 2011. 36th FEBS Congress of the Biochemistry for Tomorrows Medicine, Torino, ITALY, Jun 25-30, 2011. p. 61-61.
A. Fairlamb; S. Cole : Antimicrobial drug discovery; Future Microbiology. 2011. DOI : 10.2217/FMB.11.54.
L. Vera-Cabrera; W. G. Escalante-Fuentes; M. Gomez-Flores; J. Ocampo-Candiani; P. Busso et al. : A Case of Diffuse Lepromatous Leprosy associated with Mycobacterium lepromatosis; Journal of clinical microbiology. 2011. DOI : 10.1128/JCM.05634-11.
S. T. Cole : Microbiology. Pyrazinamide--old TB drug finds new target; Science (New York, N.Y.). 2011. DOI : 10.1126/science.1212450.
S. T. Cole; G. Riccardi : New tuberculosis drugs on the horizon; Current opinion in microbiology. 2011. DOI : 10.1016/j.mib.2011.07.022.
S. Uplekar; B. Heym; V. Friocourt; J. Rougemont; S. T. Cole : Comparative genomics of Esx genes from clinical isolates of Mycobacterium tuberculosis provides evidence for gene conversion and epitope variation; Infection and immunity. 2011. DOI : 10.1128/IAI.05344-11.
R. W. Truman; P. Singh; R. Sharma; P. Busso; J. Rougemont et al. : Probable zoonotic leprosy in the southern United States; The New England journal of medicine. 2011. DOI : 10.1056/NEJMoa1010536.
P. Singh; P. Busso; A. Paniz-Mondolfi; N. Aranzazu; M. Monot et al. : Molecular drug susceptibility testing and genotyping of Mycobacterium leprae strains from South America; Antimicrobial agents and chemotherapy. 2011. DOI : 10.1128/AAC.00201-11.
D. Bottai; L. Majlessi; R. Simeone; W. Frigui; C. Laurent et al. : ESAT-6 secretion-independent impact of ESX-1 genes espF and espG1 on virulence of Mycobacterium tuberculosis; The Journal of infectious diseases. 2011. DOI : 10.1093/infdis/jiq089.
M. A. Kirksey; A. D. Tischler; R. Siméone; K. B. Hisert; S. Uplekar et al. : Spontaneous phthiocerol dimycocerosate-deficient variants of Mycobacterium tuberculosis are susceptible to gamma interferon-mediated immunity; Infection and immunity. 2011. DOI : 10.1128/IAI.00097-11.
B. Blasco; M. Stenta; L. Alonso-Sarduy; G. Dietler; M. Dal Peraro et al. : Atypical DNA recognition mechanism used by the EspR virulence regulator of Mycobacterium tuberculosis; Molecular Microbiology. 2011. DOI : 10.1111/j.1365-2958.2011.07813.x.

2010

P. Domenech; G. S. Kolly; L. Leon-Solis; A. Fallow; M. B. Reed : Massive Gene Duplication Event among Clinical Isolates of the Mycobacterium tuberculosis W/Beijing Family; Journal Of Bacteriology. 2010. DOI : 10.1128/JB.00536-10.
N. Berthet; A. Deletoile; V. Passet; G. C. Kennedy; J.-C. Manuguerra et al. : Reconstructed ancestral sequences improve pathogen identification using resequencing DNA microarrays; PloS one. 2010. DOI : 10.1371/journal.pone.0015243.
P. Singh; S. T. Cole : Mycobacterium leprae: genes, pseudogenes and genetic diversity; Future microbiology. 2010. DOI : 10.2217/fmb.10.153.
J. M. Chen; F. Pojer; B. Blasco; S. T. Cole : Towards anti-virulence drugs targeting ESX-1 mediated pathogenesis of Mycobacterium tuberculosis; Drug Discovery Today: Disease Mechanisms. 2010. DOI : 10.1016/j.ddmec.2010.09.002.
I. Leclercq; N. Berthet; C. Batéjat; C. Rousseaux; P. Dickinson et al. : Use of consensus sequences for the design of high density resequencing microarrays: the influenza virus paradigm; BMC genomics. 2010. DOI : 10.1186/1471-2164-11-586.
J. M. Lew; A. Kapopoulou; L. M. Jones; S. T. Cole : TubercuList - 10 years after; Tuberculosis (Edinburgh, Scotland). 2010. DOI : 10.1016/j.tube.2010.09.008.
A. Kapopoulou; J. M. Lew; S. T. Cole : The MycoBrowser portal: a comprehensive and manually annotated resource for mycobacterial genomes; Tuberculosis (Edinburgh, Scotland). 2010. DOI : 10.1016/j.tube.2010.09.006.
S. Magnet; R. C. Hartkoorn; R. Székely; J. Pató; J. A. Triccas et al. : Leads for antitubercular compounds from kinase inhibitor library screens; Tuberculosis. 2010. DOI : 10.1016/j.tube.2010.09.001.
C. Trefzer; M. Rengifo-Gonzalez; M. J. Hinner; P. Schneider; V. Makarov et al. : Benzothiazinones: prodrugs that covalently modify the decaprenylphosphoryl-β-D-ribose 2'-epimerase DprE1 of Mycobacterium tuberculosis; Journal of the American Chemical Society. 2010. DOI : 10.1021/ja106357w.
C. A. Molina-Torres; J. Castro-Garza; J. Ocampo-Candiani; M. Monot; S. T. Cole et al. : Effect of serial subculturing on the genetic composition and cytotoxic activity of Mycobacterium tuberculosis; Journal of medical microbiology. 2010. DOI : 10.1099/jmm.0.015966-0.
M. R. Pasca; G. Degiacomi; A. L. d. J. L. Ribeiro; F. Zara; P. De Mori et al. : Clinical isolates of Mycobacterium tuberculosis in four European hospitals are uniformly susceptible to benzothiazinones; Antimicrobial agents and chemotherapy. 2010. DOI : 10.1128/AAC.01676-09.
S. Bonazzi; D. Barbaras; L. Patiny; R. Scopelliti; P. Schneider et al. : Antimalarial and antitubercular nostocarboline and eudistomin derivatives: synthesis, in vitro and in vivo biological evaluation; Bioorganic & medicinal chemistry. 2010. DOI : 10.1016/j.bmc.2010.01.013.
F. Boldrin; S. Casonato; E. Dainese; C. Sala; N. Dhar et al. : Development of a repressible mycobacterial promoter system based on two transcriptional repressors; Nucleic acids research. 2010. DOI : 10.1093/nar/gkq235.
L. Dacheux; N. Berthet; G. Dissard; E. C. Holmes; O. Delmas et al. : Application of broad-spectrum resequencing microarray for genotyping rhabdoviruses; Journal of virology. 2010. DOI : 10.1128/JVI.00771-10.
G. Manina; M. Bellinzoni; M. R. Pasca; J. Neres; A. Milano et al. : Biological and structural characterization of the Mycobacterium smegmatis nitroreductase NfnB, and its role in benzothiazinone resistance; Molecular microbiology. 2010. DOI : 10.1111/j.1365-2958.2010.07277.x.
V. Salzman; S. Mondino; C. Sala; S. T. Cole; G. Gago et al. : Transcriptional regulation of lipid homeostasis in mycobacteria; Molecular microbiology. 2010. DOI : 10.1111/j.1365-2958.2010.07313.x.
C. Sala; N. Dhar; R. C. Hartkoorn; M. Zhang; Y. H. Ha et al. : A Simple Model for Testing Drugs against Non-replicating Mycobacterium tuberculosis; Antimicrobial agents and chemotherapy. 2010. DOI : 10.1128/AAC.00821-10.
R. C. Hartkoorn; C. Sala; S. J. Magnet; J. M. Chen; F. Pojer et al. : Sigma Factor F does not Prevent Rifampin Inhibition of RNA Polymerase or Cause Rifampin Tolerance in Mycobacterium tuberculosis; Journal of bacteriology. 2010. DOI : 10.1128/JB.00687-10.
A. Massouras; K. Hens; C. Gubelmann; S. Uplekar; F. Decouttere et al. : Primer-initiated sequence synthesis to detect and assemble structural variants; Nature Methods. 2010. DOI : 10.1038/nmeth.f.308.

2009

M. Kaeser; O. Gutmann; J. Hauser; T. Stinear; S. Cole et al. : Lack of Insertional-Deletional Polymorphism in a Collection of Mycobacterium ulcerans Isolates from Ghanaian Buruli Ulcer Patients; Journal Of Clinical Microbiology. 2009. DOI : 10.1128/JCM.00760-09.
C. Sala; D. C. Grainger; S. T. Cole : Dissecting regulatory networks in host-pathogen interaction using chIP-on-chip technology; Cell host & microbe. 2009. DOI : 10.1016/j.chom.2009.04.007.
C. Sala; A. Haouz; F. A. Saul; I. Miras; I. Rosenkrands et al. : Genome-wide regulon and crystal structure of BlaI (Rv1846c) from Mycobacterium tuberculosis; Molecular microbiology. 2009. DOI : 10.1111/j.1365-2958.2008.06583.x.
L. Alvey; S. Prado; B. Saint-Joanis; S. Michel; M. Koch et al. : Diversity-oriented synthesis of furo[3,2-f]chromanes with antimycobacterial activity; European journal of medicinal chemistry. 2009. DOI : 10.1016/j.ejmech.2009.01.017.
M. C. Garcia Pelayo; S. Uplekar; A. Keniry; P. Mendoza Lopez; T. Garnier et al. : A comprehensive survey of single nucleotide polymorphisms (SNPs) across Mycobacterium bovis strains and M. bovis BCG vaccine strains refines the genealogy and defines a minimal set of SNPs that separate virulent M. bovis strains and M. bovis BCG strains; Infection and immunity. 2009. DOI : 10.1128/IAI.01099-08.
V. Makarov; G. Manina; K. Mikusova; U. Möllmann; O. Ryabova et al. : Benzothiazinones kill Mycobacterium tuberculosis by blocking arabinan synthesis; Science (New York, N.Y.). 2009. DOI : 10.1126/science.1171583.
C. Buchrieser; S. T. Cole : From functional genomics to systems (micro)biology; Current opinion in microbiology. 2009. DOI : 10.1016/j.mib.2009.09.001.
W. Bitter; E. N. G. Houben; D. Bottai; P. Brodin; E. J. Brown et al. : Systematic genetic nomenclature for type VII secretion systems; PLoS pathogens. 2009. DOI : 10.1371/journal.ppat.1000507.
T. Christophe; M. Jackson; H. K. Jeon; D. Fenistein; M. Contreras-Dominguez et al. : High content screening identifies decaprenyl-phosphoribose 2' epimerase as a target for intracellular antimycobacterial inhibitors; PLoS pathogens. 2009. DOI : 10.1371/journal.ppat.1000645.
M. Monot; N. Honoré; T. Garnier; N. Zidane; D. Sherafi et al. : Comparative genomic and phylogeographic analysis of Mycobacterium leprae; Nature genetics. 2009. DOI : 10.1038/ng.477.

2008

C. Sala; F. Forti; F. Magnoni; D. Ghisotti : The katG mRNA of Mycobacterium tuberculosis and Mycobacterium smegmatis is processed at its 5 ' end and is stabilized by both a polypurine sequence and translation initiation; Bmc Molecular Biology. 2008. DOI : 10.1186/1471-2199-9-33.
T. S. Balganesh; P. M. Alzari; S. T. Cole : Rising standards for tuberculosis drug development; Trends in pharmacological sciences. 2008. DOI : 10.1016/j.tips.2008.08.001.
C. Demangel; T. P. Stinear; S. T. Cole : Buruli ulcer: reductive evolution enhances pathogenicity of Mycobacterium ulcerans; Nature reviews. Microbiology. 2008. DOI : 10.1038/nrmicro2077.
S. Sinha; S. Arora; K. Kosalai; A. Namane; A. S. Pym et al. : Proteome analysis of the plasma membrane of Mycobacterium tuberculosis; Comparative and functional genomics. 2008. DOI : 10.1002/cfg.211.
R. Székely; F. Wáczek; I. Szabadkai; G. Németh; B. Hegymegi-Barakonyi et al. : A novel drug discovery concept for tuberculosis: inhibition of bacterial and host cell signalling; Immunology letters. 2008. DOI : 10.1016/j.imlet.2007.12.005.
W. Frigui; D. Bottai; L. Majlessi; M. Monot; E. Josselin et al. : Control of M. tuberculosis ESAT-6 secretion and specific T cell recognition by PhoP; PLoS pathogens. 2008. DOI : 10.1371/journal.ppat.0040033.
T. P. Stinear; T. Seemann; P. F. Harrison; G. A. Jenkin; J. K. Davies et al. : Insights from the complete genome sequence of Mycobacterium marinum on the evolution of Mycobacterium tuberculosis; Genome research. 2008. DOI : 10.1101/gr.075069.107.
M. Monot; N. Honoré; C. Balière; B. Ji; S. Sow et al. : Are variable-number tandem repeats appropriate for genotyping Mycobacterium leprae?; Journal of clinical microbiology. 2008. DOI : 10.1128/JCM.00239-08.
P. Tafelmeyer; C. Laurent; P. Lenormand; J.-C. Rousselle; L. Marsollier et al. : Comprehensive proteome analysis of Mycobacterium ulcerans and quantitative comparison of mycolactone biosynthesis; Proteomics. 2008. DOI : 10.1002/pmic.200701018.
L. Alvey; S. Prado; V. Huteau; B. Saint-Joanis; S. Michel et al. : A new synthetic access to furo[3,2-f]chromene analogues of an antimycobacterial; Bioorganic & medicinal chemistry. 2008. DOI : 10.1016/j.bmc.2008.06.057.
N. Berthet; A. K. Reinhardt; I. Leclercq; S. van Ooyen; C. Batéjat et al. : Phi29 polymerase based random amplification of viral RNA as an alternative to random RT-PCR; BMC molecular biology. 2008. DOI : 10.1186/1471-2199-9-77.
K. J. McLean; P. Carroll; D. G. Lewis; A. J. Dunford; H. E. Seward et al. : Characterization of active site structure in CYP121: A cytochrome P450 essential for viability of Mycobacterium tuberculosis H37Rv; The Journal of biological chemistry. 2008. DOI : 10.1074/jbc.M802115200.

2007

S. T. Cole; P. M. Alzari : Towards new tuberculosis drugs. 2007. Focus Topic at Life Sciences 2007 Conference, Glasgow, SCOTLAND, Jul 09-12, 2007. p. 1321-1324.
A. Wehenkel; M. Bellinzoni; M. Graña; R. Duran; A. Villarino et al. : Mycobacterial Ser/Thr protein kinases and phosphatases: physiological roles and therapeutic potential; Biochimica et biophysica acta. 2007. DOI : 10.1016/j.bbapap.2007.08.006.
S. T. Cole; P. M. Alzari : Towards new tuberculosis drugs; Biochemical Society transactions. 2007. DOI : 10.1042/BST0351321.
S. Prado; Y. L. Janin; B. Saint-Joanis; P. Brodin; S. Michel et al. : Synthesis and antimycobacterial evaluation of benzofurobenzopyran analogues; Bioorganic & medicinal chemistry. 2007. DOI : 10.1016/j.bmc.2006.12.009.
T. P. Stinear; T. Seemann; S. Pidot; W. Frigui; G. Reysset et al. : Reductive evolution and niche adaptation inferred from the genome of Mycobacterium ulcerans, the causative agent of Buruli ulcer; Genome research. 2007. DOI : 10.1101/gr.5942807.
L. Marsollier; E. Deniaux; P. Brodin; A. Marot; C. M. Wondje et al. : Protection against Mycobacterium ulcerans lesion development by exposure to aquatic insect saliva; PLoS medicine. 2007. DOI : 10.1371/journal.pmed.0040064.
R. Brosch; S. V. Gordon; T. Garnier; K. Eiglmeier; W. Frigui et al. : Genome plasticity of BCG and impact on vaccine efficacy; Proceedings of the National Academy of Sciences of the United States of America. 2007. DOI : 10.1073/pnas.0700869104.
J. Teutschbein; G. Schumann; U. Möllmann; S. Grabley; S. T. Cole et al. : A protein linkage map of the ESAT-6 secretion system 1 (ESX-1) of Mycobacterium tuberculosis; Microbiological research. 2007. DOI : 10.1016/j.micres.2006.11.016.
L. Marsollier; P. Brodin; M. Jackson; J. Korduláková; P. Tafelmeyer et al. : Impact of Mycobacterium ulcerans biofilm on transmissibility to ecological niches and Buruli ulcer pathogenesis; PLoS pathogens. 2007. DOI : 10.1371/journal.ppat.0030062.
E. Coutanceau; J. Decalf; A. Martino; A. Babon; N. Winter et al. : Selective suppression of dendritic cell functions by Mycobacterium ulcerans toxin mycolactone; The Journal of experimental medicine. 2007. DOI : 10.1084/jem.20070234.
M. I. de Jonge; G. Pehau-Arnaudet; M. M. Fretz; F. Romain; D. Bottai et al. : ESAT-6 from Mycobacterium tuberculosis dissociates from its putative chaperone CFP-10 under acidic conditions and exhibits membrane-lysing activity; Journal of bacteriology. 2007. DOI : 10.1128/JB.00469-07.
M. Graña; A. Haouz; A. Buschiazzo; I. Miras; A. Wehenkel et al. : The crystal structure of M. leprae ML2640c defines a large family of putative S-adenosylmethionine-dependent methyltransferases in mycobacteria; Protein science : a publication of the Protein Society. 2007. DOI : 10.1110/ps.072982707.
M. Casenghi; S. T. Cole; C. F. Nathan : New approaches to filling the gap in tuberculosis drug discovery; PLoS medicine. 2007. DOI : 10.1371/journal.pmed.0040293.
M.-L. Chesne-Seck; N. Barilone; F. Boudou; J. Gonzalo Asensio; P. E. Kolattukudy et al. : A point mutation in the two-component regulator PhoP-PhoR accounts for the absence of polyketide-derived acyltrehaloses but not that of phthiocerol dimycocerosates in Mycobacterium tuberculosis H37Ra; Journal of bacteriology. 2007. DOI : 10.1128/JB.01465-07.

2006

L. Majlessi; M. Simsova; Z. Jarvis; P. Brodin; M.-J. Rojas et al. : An increase in antimycobacterial Th1-cell responses by prime-boost protocols of immunization does not enhance protection against tuberculosis; Infection and immunity. 2006. DOI : 10.1128/IAI.74.4.2128-2137.2006.
S. Prado; H. Ledeit; S. Michel; M. Koch; J. C. Darbord et al. : Benzofuro[3,2-f][1]benzopyrans: a new class of antitubercular agents; Bioorganic & medicinal chemistry. 2006. DOI : 10.1016/j.bmc.2006.03.033.
E. Coutanceau; P. Legras; L. Marsollier; G. Reysset; S. T. Cole et al. : Immunogenicity of Mycobacterium ulcerans Hsp65 and protective efficacy of a Mycobacterium leprae Hsp65-based DNA vaccine against Buruli ulcer; Microbes and infection / Institut Pasteur. 2006. DOI : 10.1016/j.micinf.2006.03.009.
R. Aráoz; N. Honoré; S. Banu; C. Demangel; Y. Cissoko et al. : Towards an immunodiagnostic test for leprosy; Microbes and infection / Institut Pasteur. 2006. DOI : 10.1016/j.micinf.2006.04.002.
B. Saint-Joanis; C. Demangel; M. Jackson; P. Brodin; L. Marsollier et al. : Inactivation of Rv2525c, a substrate of the twin arginine translocation (Tat) system of Mycobacterium tuberculosis, increases beta-lactam susceptibility and virulence; Journal of bacteriology. 2006. DOI : 10.1128/JB.00631-06.
P. Fernandez; B. Saint-Joanis; N. Barilone; M. Jackson; B. Gicquel et al. : The Ser/Thr protein kinase PknB is essential for sustaining mycobacterial growth; Journal of bacteriology. 2006. DOI : 10.1128/JB.00963-06.
L. Marsollier; J.-P. S. André; W. Frigui; G. Reysset; G. Milon et al. : Early trafficking events of Mycobacterium ulcerans within Naucoris cimicoides; Cellular microbiology. 2006. DOI : 10.1111/j.1462-5822.2006.00790.x.
W. Shepard; A. Haouz; M. Graña; A. Buschiazzo; J.-M. Betton et al. : The crystal structure of Rv0813c from Mycobacterium tuberculosis reveals a new family of fatty acid-binding protein-like proteins in bacteria; Journal of bacteriology. 2006. DOI : 10.1128/JB.01435-06.

2005

P. Brodin; C. Demangel; S. T. Cole : Introduction to functional genomics of the Mycobacterium tuberculosis Complex; Tuberculosis and the tubercle bacillus; Washington, D.C: ASM Press, 2005. p. 143-153.
S. H. E. Kaufmann; S. T. Cole; V. Mizrahi; E. Rubin; C. Nathan : Mycobacterium tuberculosis and the host response; The Journal of experimental medicine. 2005. DOI : 10.1084/jem.20050842.
M. I. de Jonge; R. Brosch; P. Brodin; C. Demangel; S. T. Cole : Tuberculosis: from genome to vaccine; Expert review of vaccines. 2005. DOI : 10.1586/14760584.4.4.541.
S. T. Cole; P. M. Alzari : Microbiology. TB--a new target, a new drug; Science (New York, N.Y.). 2005. DOI : 10.1126/science.1108379.
A. Williams; G. J. Hatch; S. O. Clark; K. E. Gooch; K. A. Hatch et al. : Evaluation of vaccines in the EU TB Vaccine Cluster using a guinea pig aerosol infection model of tuberculosis; Tuberculosis (Edinburgh, Scotland). 2005. DOI : 10.1016/j.tube.2004.09.009.
T. P. Stinear; H. Hong; W. Frigui; M. J. Pryor; R. Brosch et al. : Common evolutionary origin for the unstable virulence plasmid pMUM found in geographically diverse strains of Mycobacterium ulcerans; Journal of bacteriology. 2005. DOI : 10.1128/JB.187.5.1668-1676.2005.
L. Majlessi; P. Brodin; R. Brosch; M.-J. Rojas; H. Khun et al. : Influence of ESAT-6 secretion system 1 (RD1) of Mycobacterium tuberculosis on the interaction between mycobacteria and the host immune system; Journal of immunology (Baltimore, Md. : 1950). 2005. DOI : 10.4049/​jimmunol.174.6.3570.
T. P. Stinear; M. J. Pryor; J. L. Porter; S. T. Cole : Functional analysis and annotation of the virulence plasmid pMUM001 from Mycobacterium ulcerans; Microbiology (Reading, England). 2005. DOI : 10.1099/mic.0.27674-0.
C. Demangel; T. Garnier; I. Rosenkrands; S. T. Cole : Differential effects of prior exposure to environmental mycobacteria on vaccination with Mycobacterium bovis BCG or a recombinant BCG strain expressing RD1 antigens; Infection and immunity. 2005. DOI : 10.1128/IAI.73.4.2190-2196.2005.
B. G. Guimarães; H. Souchon; N. Honoré; B. Saint-Joanis; R. Brosch et al. : Structure and mechanism of the alkyl hydroperoxidase AhpC, a key element of the Mycobacterium tuberculosis defense system against oxidative stress; The Journal of biological chemistry. 2005. DOI : 10.1074/jbc.M503076200.
M. Monot; N. Honoré; T. Garnier; R. Araoz; J.-Y. Coppée et al. : On the origin of leprosy; Science (New York, N.Y.). 2005. DOI : 10.1126/science/1109759.
L. Marsollier; J. Aubry; E. Coutanceau; J.-P. S. André; P. L. Small et al. : Colonization of the salivary glands of Naucoris cimicoides by Mycobacterium ulcerans requires host plasmatocytes and a macrolide toxin, mycolactone; Cellular microbiology. 2005. DOI : 10.1111/j.1462-5822.2005.00521.x.
R. Durán; A. Villarino; M. Bellinzoni; A. Wehenkel; P. Fernandez et al. : Conserved autophosphorylation pattern in activation loops and juxtamembrane regions of Mycobacterium tuberculosis Ser/Thr protein kinases; Biochemical and biophysical research communications. 2005. DOI : 10.1016/j.bbrc.2005.05.173.
A. Villarino; R. Duran; A. Wehenkel; P. Fernandez; P. England et al. : Proteomic identification of M. tuberculosis protein kinase substrates: PknB recruits GarA, a FHA domain-containing protein, through activation loop-mediated interactions; Journal of molecular biology. 2005. DOI : 10.1016/j.jmb.2005.05.049.
S. Sinha; K. Kosalai; S. Arora; A. Namane; P. Sharma et al. : Immunogenic membrane-associated proteins of Mycobacterium tuberculosis revealed by proteomics; Microbiology (Reading, England). 2005. DOI : 10.1099/mic.0.27799-0.
E. Coutanceau; L. Marsollier; R. Brosch; E. Perret; P. Goossens et al. : Modulation of the host immune response by a transient intracellular stage of Mycobacterium ulcerans: the contribution of endogenous mycolactone toxin; Cellular microbiology. 2005. DOI : 10.1111/j.1462-5822.2005.00546.x.
P. Brodin; M. I. de Jonge; L. Majlessi; C. Leclerc; M. Nilges et al. : Functional analysis of early secreted antigenic target-6, the dominant T-cell antigen of Mycobacterium tuberculosis, reveals key residues involved in secretion, complex formation, virulence, and immunogenicity; The Journal of biological chemistry. 2005. DOI : 10.1074/jbc.M503515200.
J. S. Spencer; H. M. Dockrell; H. J. Kim; M. A. M. Marques; D. L. Williams et al. : Identification of specific proteins and peptides in mycobacterium leprae suitable for the selective diagnosis of leprosy; Journal of immunology (Baltimore, Md. : 1950). 2005. DOI : 10.4049/jimmunol.175.12.7930.
P. Brodin; L. Majlessi; L. Marsollier; M. I. de Jonge; D. Bottai et al. : Dissection of ESAT-6 system 1 of Mycobacterium tuberculosis and impact on immunogenicity and virulence; Infection and immunity. 2005. DOI : 10.1128/IAI.74.1.88-98.2006.
R. Aráoz; N. Honoré; S. Cho; J.-P. Kim; S.-N. Cho et al. : Antigen discovery: a postgenomic approach to leprosy diagnosis; Infection and immunity. 2005. DOI : 10.1128/IAI.74.1.175-182.2006.

2004

R. Brosch; S. Banu; S. T. Cole : Comparative genomics of the Mycobacterium tuberculosis complex: evolutionary insights and applications; Tuberculosis; Philadelphia: Lippincott Williams & Wilkins, 2004. p. 65-73.
S. D. Bentley; R. Brosch; S. V. Gordon; D. A. Hopwood; S. T. Cole : Genomics of Actinobacteria, the high G+C gram-positive bacteria; Microbial genomes; Totowa, N. J.: Humana Press, 2004. p. 333-360.
P. Brodin; I. Rosenkrands; P. Andersen; S. T. Cole; R. Brosch : ESAT-6 proteins: protective antigens and virulence factors?; Trends in microbiology. 2004. DOI : 10.1016/j.tim.2004.09.007.
T. P. Stinear; A. Mve-Obiang; P. L. C. Small; W. Frigui; M. J. Pryor et al. : Giant plasmid-encoded polyketide synthases produce the macrolide toxin of Mycobacterium ulcerans; Proceedings of the National Academy of Sciences of the United States of America. 2004. DOI : 10.1073/pnas.0305877101.
S. Banu; S. V. Gordon; S. Palmer; M. R. Islam; S. Ahmed et al. : Genotypic analysis of Mycobacterium tuberculosis in Bangladesh and prevalence of the Beijing strain; Journal of clinical microbiology. 2004. DOI : 10.1128/JCM.42.2.674-682.2004.
M. Marmiesse; P. Brodin; C. Buchrieser; C. Gutierrez; N. Simoes et al. : Macro-array and bioinformatic analyses reveal mycobacterial 'core' genes, variation in the ESAT-6 gene family and new phylogenetic markers for the Mycobacterium tuberculosis complex; Microbiology (Reading, England). 2004. DOI : 10.1099/mic.0.26662-0.
C. Demangel; P. Brodin; P. J. Cockle; R. Brosch; L. Majlessi et al. : Cell envelope protein PPE68 contributes to Mycobacterium tuberculosis RD1 immunogenicity independently of a 10-kilodalton culture filtrate protein and ESAT-6; Infection and immunity. 2004. DOI : 10.1128/IAI.72.4.2170-2176.2004.
J. S. Spencer; H. J. Kim; A. M. Marques; M. Gonzalez-Juarerro; M. C. B. S. Lima et al. : Comparative analysis of B- and T-cell epitopes of Mycobacterium leprae and Mycobacterium tuberculosis culture filtrate protein 10; Infection and immunity. 2004. DOI : 10.1128/IAI.72.6.3161-3170.2004.
P. Brodin; L. Majlessi; R. Brosch; D. Smith; G. Bancroft et al. : Enhanced protection against tuberculosis by vaccination with recombinant Mycobacterium microti vaccine that induces T cell immunity against region of difference 1 antigens; The Journal of infectious diseases. 2004. DOI : 10.1086/421468.
L. Marsollier; T. Sévérin; J. Aubry; R. W. Merritt; J.-P. Saint André et al. : Aquatic snails, passive hosts of Mycobacterium ulcerans; Applied and environmental microbiology. 2004. DOI : 10.1128/AEM.70.10.6296-6298.2004.
C. Demangel; R. Brosch; M. Marmiesse; S. T. Cole : [Use of the mycobacteria genome to develop new vaccines and therapeutic targets]; Médecine tropicale : revue du Corps de santé colonial. 2004.

2003

L. Marsollier; N. Honoré; P. Legras; A. L. Manceau; H. Kouakou et al. : Isolation of three Mycobacterium ulcerans strains resistant to rifampin after experimental chemotherapy of mice; Antimicrobial agents and chemotherapy. 2003. DOI : 10.1128/AAC.47.4.1228-1232.2003.
A. S. Pym; P. Brodin; L. Majlessi; R. Brosch; C. Demangel et al. : Recombinant BCG exporting ESAT-6 confers enhanced protection against tuberculosis; Nature medicine. 2003. DOI : 10.1038/nm859.
S. R. Krutzik; M. T. Ochoa; P. A. Sieling; S. Uematsu; Y. W. Ng et al. : Activation and regulation of Toll-like receptors 2 and 1 in human leprosy; Nature medicine. 2003. DOI : 10.1038/nm864.
T. Garnier; K. Eiglmeier; J.-C. Camus; N. Medina; H. Mansoor et al. : The complete genome sequence of Mycobacterium bovis; Proceedings of the National Academy of Sciences of the United States of America. 2003. DOI : 10.1073/pnas.1130426100.
B. Boitel; M. Ortiz-Lombardía; R. Durán; F. Pompeo; S. T. Cole et al. : PknB kinase activity is regulated by phosphorylation in two Thr residues and dephosphorylation by PstP, the cognate phospho-Ser/Thr phosphatase, in Mycobacterium tuberculosis; Molecular microbiology. 2003. DOI : 10.1046/j.1365-2958.2003.03657.x.
H. Hong; P. J. Gates; J. Staunton; T. Stinear; S. T. Cole et al. : Identification using LC-MSn of co-metabolites in the biosynthesis of the polyketide toxin mycolactone by a clinical isolate of Mycobacterium ulcerans; Chemical communications (Cambridge, England). 2003. DOI : 10.1039/b308163j.

2002

K. Eiglmeier; J. Parkhill; N. Honoré; T. Garnier; F. Tekaia et al. : The decaying genome of Mycobacterium leprae; Leprosy review. 2002.
J. H. Grosset; S. T. Cole : Genomics and the chemotherapy of leprosy; Leprosy review. 2002.
K. Eiglmeier; S. Simon; T. Garnier; S. T. Cole : The integrated genome map of Mycobacterium leprae; Leprosy review. 2002.
S. T. Cole : Comparative mycobacterial genomics as a tool for drug target and antigen discovery; The European respiratory journal. Supplement. 2002.
S. T. Cole : Comparative and functional genomics of the Mycobacterium tuberculosis complex; Microbiology (Reading, England). 2002.
N. Honoré; P. W. Roche; J. H. Grosset; S. T. Cole : A method for rapid detection of rifampicin-resistant isolates of Mycobacterium leprae.; Leprosy review. 2002.
S. T. Cole; P. Supply; N. Honoré : Repetitive sequences in Mycobacterium leprae and their impact on genome plasticity.; Leprosy review. 2002.
P. Domenech; A. S. Pym; M. Cellier; C. E. Barry; S. T. Cole : Inactivation of the Mycobacterium tuberculosis Nramp orthologue (mntH) does not affect virulence in a mouse model of tuberculosis; FEMS microbiology letters. 2002. DOI : 10.1111/j.1574-6968.2002.tb11032.x.
R. Brosch; S. V. Gordon; M. Marmiesse; P. Brodin; C. Buchrieser et al. : A new evolutionary scenario for the Mycobacterium tuberculosis complex; Proceedings of the National Academy of Sciences of the United States of America. 2002. DOI : 10.1073/pnas.052548299.
S. V. Gordon; R. Brosch; K. Eiglmeier; T. Garnier; R. G. Hewinson et al. : Mycobacterial genomics; Transactions of the Royal Society of Tropical Medicine and Hygiene. 2002. DOI : 10.1016/S0035-9203(02)90222-1.
S. Banu; N. Honoré; B. Saint-Joanis; D. Philpott; M.-C. Prévost et al. : Are the PE-PGRS proteins of Mycobacterium tuberculosis variable surface antigens?; Molecular microbiology. 2002. DOI : 10.1046/j.1365-2958.2002.02813.x.
L. M. Parsons; R. Brosch; S. T. Cole; A. Somoskövi; A. Loder et al. : Rapid and simple approach for identification of Mycobacterium tuberculosis complex isolates by PCR-based genomic deletion analysis; Journal of clinical microbiology. 2002. DOI : 10.1128/JCM.40.7.2339-2345.2002.
A. S. Pym; B. Saint-Joanis; S. T. Cole : Effect of katG mutations on the virulence of Mycobacterium tuberculosis and the implication for transmission in humans; Infection and immunity. 2002. DOI : 10.1128/IAI.70.9.4955-4960.2002.
P. Brodin; K. Eiglmeier; M. Marmiesse; A. Billault; T. Garnier et al. : Bacterial artificial chromosome-based comparative genomic analysis identifies Mycobacterium microti as a natural ESAT-6 deletion mutant; Infection and immunity. 2002. DOI : 10.1128/IAI.70.10.5568-5578.2002.
J.-C. Camus; M. J. Pryor; C. Médigue; S. T. Cole : Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv; Microbiology (Reading, England). 2002. DOI : 10.1099/00221287-148-10-2967.
A. S. Pym; P. Brodin; R. Brosch; M. Huerre; S. T. Cole : Loss of RD1 contributed to the attenuation of the live tuberculosis vaccines Mycobacterium bovis BCG and Mycobacterium microti; Molecular microbiology. 2002. DOI : 10.1046/j.1365-2958.2002.03237.x.

2001

P. Domenech; C. E. Barry; S. T. Cole : Mycobacterium tuberculosis in the post-genomic age; Current opinion in microbiology. 2001.
S. T. Cole; N. Honore; K. Eiglmeier : Preliminary analysis of the genome sequence of Mycobacterium leprae; Leprosy review. 2001.
S. V. Gordon; K. Eiglmeier; T. Garnier; R. Brosch; J. Parkhill et al. : Genomics of Mycobacterium bovis; Tuberculosis (Edinburgh, Scotland). 2001. DOI : 10.1054/tube.2000.0269.
R. Brosch; A. S. Pym; S. V. Gordon; S. T. Cole : The evolution of mycobacterial pathogenicity: clues from comparative genomics; Trends in microbiology. 2001.
P. W. Roche; N. Shrestha; A. Thomas; N. Honore; S. T. Cole : Rapid detection of resistance to rifampicin in Mycobacterium leprae.; Leprosy review. 2001.
S. T. Cole; K. Eiglmeier; J. Parkhill; K. D. James; N. R. Thomson et al. : Massive gene decay in the leprosy bacillus; Nature. 2001. DOI : 10.1038/35059006.
A. S. Pym; P. Domenech; N. Honoré; J. Song; V. Deretic et al. : Regulation of catalase-peroxidase (KatG) expression, isoniazid sensitivity and virulence by furA of Mycobacterium tuberculosis; Molecular microbiology. 2001. DOI : 10.1046/j.1365-2958.2001.02427.x.
M. Sofia; M. Maniscalco; N. Honoré; A. Molino; M. Mormile et al. : Familial outbreak of disseminated multidrug-resistant tuberculosis and meningitis; The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease. 2001.
P. Domenech; N. Honoré; B. Heym; S. T. Cole : Role of OxyS of Mycobacterium tuberculosis in oxidative stress: overexpression confers increased sensitivity to organic hydroperoxides; Microbes and infection / Institut Pasteur. 2001. DOI : 10.1016/S1286-4579(01)01422-8.
L. Jones; I. Moszer; S. T. Cole : Leproma: a Mycobacterium leprae genome browser.; Leprosy review. 2001.

2000

B. Heym; B. Saint-Joanis; S. T. Cole : The molecular basis of isoniazid resistance in Mycobacterium tuberculosis; Tubercle and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease. 2000.
R. Brosch; S. V. Gordon; K. Eiglmeier; T. Garnier; S. T. Cole : Comparative genomics of the leprosy and tubercle bacilli; Research in microbiology. 2000.
R. Brosch; S. V. Gordon; A. Pym; K. Eiglmeier; T. Garnier et al. : Comparative genomics of the mycobacteria; International journal of medical microbiology : IJMM. 2000.
S. T. Cole : [What can be expected from sequencing of the Mycobacterium tuberculosis genome?]; Bulletin de l'Académie nationale de médecine. 2000.
S. Banu; K. Ohtani; H. Yaguchi; T. Swe; S. T. Cole et al. : Identification of novel VirR/VirS-regulated genes in Clostridium perfringens; Molecular microbiology. 2000. DOI : 10.1046/j.1365-2958.2000.01760.x.
F. Tekaia; S. V. Gordon; T. Garnier; R. Brosch; B. G. Barrell et al. : Analysis of the proteome of Mycobacterium tuberculosis in silico; Tubercle and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease. 2000. DOI : 10.1054/tuld.1999.0220.
H. Makui; E. Roig; S. T. Cole; J. D. Helmann; P. Gros et al. : Identification of the Escherichia coli K-12 Nramp orthologue (MntH) as a selective divalent metal ion transporter; Molecular microbiology. 2000. DOI : 10.1046/j.1365-2958.2000.01774.x.
R. Brosch; S. V. Gordon; C. Buchrieser; A. S. Pym; T. Garnier et al. : Comparative genomics uncovers large tandem chromosomal duplications in Mycobacterium bovis BCG Pasteur; Yeast (Chichester, England). 2000. DOI : 10.1002/1097-0061(20000630)17:2<111::AID-YEA17>3.0.CO;2-G.
A. Alape-Girón; M. Flores-Díaz; I. Guillouard; C. E. Naylor; R. W. Titball et al. : Identification of residues critical for toxicity in Clostridium perfringens phospholipase C, the key toxin in gas gangrene; European journal of biochemistry / FEBS. 2000. DOI : 10.1046/j.1432-1327.2000.01588.x.

1999

S. T. Cole; B. G. Barrell : Analysis of the genome of Mycobacterium tuberculosis H37Rv; Novartis Foundation symposium. 1999.
S. T. Cole : Comparative mycobacterial genomics; Current opinion in microbiology. 1999.
S. T. Cole : Learning from the genome sequence of Mycobacterium tuberculosis H37Rv; FEBS letters. 1999.
S. T. Cole : [The study of the genome of Mycobacterium leprae]; Acta leprologica. 1999.
W. J. Philipp; S. Gordon; A. Telenti; S. T. Cole : Pulsed field gel electrophoresis for mycobacteria; Mycobacteria Protocols; Totowa, NJ: Humana Press, 1999. p. 51-63.
S. Bergh; S. T. Cole : Using MycDB on the World-Wide Web; Mycobacteria Protocols; Totowa, NJ: Humana Press, 1999. p. 109-18.
A. Telenti; N. Honoré; S. T. Cole : Detection of mutations in mycobacteria by PCR-SSCP (single-strand conformation polymorphism); Mycobacteria Protocols; Totowa, NJ: Humana Press, 1999. p. 423-430.
B. Saint-Joanis; H. Souchon; M. Wilming; K. Johnsson; P. M. Alzari et al. : Use of site-directed mutagenesis to probe the structure, function and isoniazid activation of the catalase/peroxidase, KatG, from Mycobacterium tuberculosis; The Biochemical journal. 1999. DOI : 10.1042/0264-6021:3380753.
S. V. Gordon; B. Heym; J. Parkhill; B. Barrell; S. T. Cole : New insertion sequences and a novel repeated sequence in the genome of Mycobacterium tuberculosis H37Rv; Microbiology (Reading, England). 1999. DOI : 10.1099/13500872-145-4-881.
S. V. Gordon; R. Brosch; A. Billault; T. Garnier; K. Eiglmeier et al. : Identification of variable regions in the genomes of tubercle bacilli using bacterial artificial chromosome arrays.; Molecular microbiology. 1999. DOI : 10.1046/j.1365-2958.1999.01383.x.
S. T. Cole : The Mycobacterium leprae genome project; International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association. 1999.
T. Lichtinger; B. Heym; E. Maier; H. Eichner; S. T. Cole et al. : Evidence for a small anion-selective channel in the cell wall of Mycobacterium bovis BCG besides a wide cation-selective pore; FEBS letters. 1999. DOI : 10.1016/S0014-5793(99)00844-3.
A. S. Pym; S. T. Cole : Post DOTS, post genomics: the next century of tuberculosis control; Lancet. 1999. DOI : 10.1016/S0140-6736(99)02118-2.
R. Brosch; W. J. Philipp; E. Stavropoulos; M. J. Colston; S. T. Cole et al. : Genomic analysis reveals variation between Mycobacterium tuberculosis H37Rv and the attenuated M. tuberculosis H37Ra strain; Infection and immunity. 1999.

1998

W. J. Philipp; D. C. Schwartz; A. Telenti; S. T. Cole : Mycobacterial genome structure; Electrophoresis. 1998. DOI : 10.1002/elps.1150190418.
I. Guillouard; P. M. Alzari; B. Saliou; S. T. Cole : The carboxy-terminal C2-like domain of the alpha-toxin from Clostridium perfringens mediates calcium-dependent membrane recognition; Molecular microbiology. 1998. DOI : 10.1046/j.1365-2958.1997.6161993.x.
R. Brosch; S. V. Gordon; A. Billault; T. Garnier; K. Eiglmeier et al. : Use of a Mycobacterium tuberculosis H37Rv bacterial artificial chromosome library for genome mapping, sequencing, and comparative genomics; Infection and immunity. 1998.
S. T. Cole; R. Brosch; J. Parkhill; T. Garnier; C. Churcher et al. : Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence; Nature. 1998. DOI : 10.1038/31159.
F. S. Silbaq; S. N. Cho; S. T. Cole; P. J. Brennan : Characterization of a 34-kilodalton protein of Mycobacterium leprae that is isologous to the immunodominant 34-kilodalton antigen of Mycobacterium paratuberculosis; Infection and immunity. 1998.

1997

B. Heym; S. T. Cole : Multidrug resistance in Mycobacterium tuberculosis; International journal of antimicrobial agents. 1997. DOI : 10.1016/S0924-8579(96)00356-1.
A. Telenti; N. Honoré; C. Bernasconi; J. March; A. Ortega et al. : Genotypic assessment of isoniazid and rifampin resistance in Mycobacterium tuberculosis: a blind study at reference laboratory level.; Journal of clinical microbiology. 1997.
B. Heym; E. Stavropoulos; N. Honoré; P. Domenech; B. Saint-Joanis et al. : Effects of overexpression of the alkyl hydroperoxide reductase AhpC on the virulence and isoniazid resistance of Mycobacterium tuberculosis.; Infection and immunity. 1997.
K. Eiglmeier; H. Fsihi; B. Heym; S. T. Cole : On the catalase-peroxidase gene, katG, of Mycobacterium leprae and the implications for treatment of leprosy with isoniazid; FEMS microbiology letters. 1997. DOI : 10.1111/j.1574-6968.1997.tb10340.x.
B. Dupuy; G. Daube; M. R. Popoff; S. T. Cole : Clostridium perfringens urease genes are plasmid borne.; Infection and immunity. 1997.
S. Lepage; P. Dubois; T. K. Ghosh; B. Joris; S. Mahapatra et al. : Dual multimodular class A penicillin-binding proteins in Mycobacterium leprae.; Journal of bacteriology. 1997. DOI : 10.1128/jb.179.14.4627-4630.1997.
D. R. Smith; P. Richterich; M. Rubenfield; P. W. Rice; C. Butler et al. : Multiplex sequencing of 1.5 Mb of the Mycobacterium leprae genome; Genome research. 1997. DOI : 10.1101/gr.7.8.802.

1996

S. T. Cole : Rifamycin resistance in mycobacteria; Research in microbiology. 1996.
B. Heym; W. Philipp; S. T. Cole : Mechanisms of drug resistance in Mycobacterium tuberculosis; Current topics in microbiology and immunology. 1996.
S. T. Cole : Why sequence the genome of Mycobacterium tuberculosis?; Tubercle and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease. 1996.
J. Basu; S. Mahapatra; M. Kundu; S. Mukhopadhyay; M. Nguyen-Distèche et al. : Identification and overexpression in Escherichia coli of a Mycobacterium leprae gene, pon1, encoding a high-molecular-mass class A penicillin-binding protein, PBP1.; Journal of bacteriology. 1996. DOI : 10.1128/jb.178.6.1707-1711.1996.
P. Chemouilli; S. Woods; G. Said; S. T. Cole : Detection of Mycobacterium leprae in nerve lesions by the polymerase chain reaction; International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association. 1996.
L. Salazar; H. Fsihi; E. de Rossi; G. Riccardi; C. Rios et al. : Organization of the origins of replication of the chromosomes of Mycobacterium smegmatis, Mycobacterium leprae and Mycobacterium tuberculosis and isolation of a functional origin from M. smegmatis; Molecular microbiology. 1996. DOI : 10.1111/j.1365-2958.1996.tb02617.x.
W. J. Philipp; S. Poulet; K. Eiglmeier; L. Pascopella; V. Balasubramanian et al. : An integrated map of the genome of the tubercle bacillus, Mycobacterium tuberculosis H37Rv, and comparison with Mycobacterium leprae; Proceedings of the National Academy of Sciences of the United States of America. 1996. DOI : 10.1073/pnas.93.7.3132.
H. Fsihi; V. Vincent; S. T. Cole : Homing events in the gyrA gene of some mycobacteria; Proceedings of the National Academy of Sciences of the United States of America. 1996. DOI : 10.1073/pnas.93.8.3410.
I. Guillouard; T. Garnier; S. T. Cole : Use of site-directed mutagenesis to probe structure-function relationships of alpha-toxin from Clostridium perfringens.; Infection and immunity. 1996.
S. Katayama; B. Dupuy; G. Daube; B. China; S. T. Cole : Genome mapping of Clostridium perfringens strains with I-CeuI shows many virulence genes to be plasmid-borne; Molecular & general genetics : MGG. 1996. DOI : 10.1007/BF02174122.
W. J. Philipp; S. Nair; G. Guglielmi; M. Lagranderie; B. Gicquel et al. : Physical mapping of Mycobacterium bovis BCG pasteur reveals differences from the genome map of Mycobacterium tuberculosis H37Rv and from M. bovis; Microbiology (Reading, England). 1996. DOI : 10.1099/13500872-142-11-3135.
H. Fsihi; E. De Rossi; L. Salazar; R. Cantoni; M. Labò et al. : Gene arrangement and organization in a approximately 76 kb fragment encompassing the oriC region of the chromosome of Mycobacterium leprae; Microbiology (Reading, England). 1996. DOI : 10.1099/13500872-142-11-3147.

1995

S. Poulet; S. T. Cole : Repeated DNA sequences in mycobacteria; Archives of microbiology. 1995.
S. T. Cole; A. Telenti : Drug resistance in Mycobacterium tuberculosis; The European respiratory journal. Supplement. 1995.
B. Heym; P. M. Alzari; N. Honoré; S. T. Cole : Missense mutations in the catalase-peroxidase gene, katG, are associated with isoniazid resistance in Mycobacterium tuberculosis; Molecular microbiology. 1995. DOI : 10.1111/j.1365-2958.1995.tb02238.x.
S. Poulet; S. T. Cole : Characterization of the highly abundant polymorphic GC-rich-repetitive sequence (PGRS) present in Mycobacterium tuberculosis; Archives of microbiology. 1995. DOI : 10.1007/BF00381781.
E. Cornillot; B. Saint-Joanis; G. Daube; S. Katayama; P. E. Granum et al. : The enterotoxin gene (cpe) of Clostridium perfringens can be chromosomal or plasmid-borne; Molecular microbiology. 1995. DOI : 10.1111/j.1365-2958.1995.tb02373.x.
N. Honoré; G. Marchal; S. T. Cole : Novel mutation in 16S rRNA associated with streptomycin dependence in Mycobacterium tuberculosis.; Antimicrobial agents and chemotherapy. 1995. DOI : 10.1128/AAC.39.3.769.
H. Fsihi; S. T. Cole : The Mycobacterium leprae genome: systematic sequence analysis identifies key catabolic enzymes, ATP-dependent transport systems and a novel polA locus associated with genomic variability; Molecular microbiology. 1995. DOI : 10.1111/j.1365-2958.1995.tb02317.x.
V. Deretic; W. Philipp; S. Dhandayuthapani; M. H. Mudd; R. Curcic et al. : Mycobacterium tuberculosis is a natural mutant with an inactivated oxidative-stress regulatory gene: implications for sensitivity to isoniazid; Molecular microbiology. 1995. DOI : 10.1111/j.1365-2958.1995.mmi_17050889.x.
S. Katayama; B. Dupuy; T. Garnier; S. T. Cole : Rapid expansion of the physical and genetic map of the chromosome of Clostridium perfringens CPN50.; Journal of bacteriology. 1995. DOI : 10.1128/jb.177.19.5680-5685.1995.
W. J. Philipp; S. T. Cole : Local comparison of the genomes of Mycobacterium tuberculosis and Mycobacterium leprae using the polymerase chain reaction; FEMS microbiology letters. 1995. DOI : 10.1111/j.1574-6968.1995.tb07844.x.
L. Doukhan; M. Predich; G. Nair; O. Dussurget; I. Mandic-Mulec et al. : Genomic organization of the mycobacterial sigma gene cluster; Gene. 1995. DOI : 10.1016/0378-1119(95)00427-8.

1994

S. T. Cole; I. Saint Girons : Bacterial genomics; FEMS microbiology reviews. 1994.
N. Honoré; S. T. Cole : Streptomycin resistance in mycobacteria.; Antimicrobial agents and chemotherapy. 1994.
H. E. Takiff; L. Salazar; C. Guerrero; W. Philipp; W. M. Huang et al. : Cloning and nucleotide sequence of Mycobacterium tuberculosis gyrA and gyrB genes and detection of quinolone resistance mutations.; Antimicrobial agents and chemotherapy. 1994. DOI : 10.1128/AAC.38.4.773.
B. Canard; T. Garnier; B. Saint-Joanis; S. T. Cole : Molecular genetic analysis of the nagH gene encoding a hyaluronidase of Clostridium perfringens.; Molecular & general genetics : MGG. 1994.
S. Bergh; S. T. Cole : MycDB: an integrated mycobacterial database; Molecular microbiology. 1994. DOI : 10.1111/j.1365-2958.1994.tb01039.x.
M. C. Pessolani; D. R. Smith; B. Rivoire; J. McCormick; S. A. Hefta et al. : Purification, characterization, gene sequence, and significance of a bacterioferritin from Mycobacterium leprae.; The Journal of experimental medicine. 1994. DOI : 10.1084/jem.180.1.319.
B. Heym; N. Honoré; C. Truffot-Pernot; A. Banerjee; C. Schurra et al. : Implications of multidrug resistance for the future of short-course chemotherapy of tuberculosis: a molecular study; Lancet. 1994. DOI : 10.1016/S0140-6736(94)91338-2.
S. T. Cole : Mechanisms of drug resistance in Mycobacterium tuberculosis; Immunobiology. 1994. DOI : 10.1016/S0171-2985(11)80466-3.
S. T. Cole : Mycobacterium tuberculosis: drug-resistance mechanisms; Trends in microbiology. 1994. DOI : 10.1016/0966-842X(94)90621-1.

1993

D. B. Young; S. T. Cole : Leprosy, tuberculosis, and the new genetics; Journal of bacteriology. 1993.
K. Eiglmeier; N. Honoré; S. A. Woods; B. Caudron; S. T. Cole : Use of an ordered cosmid library to deduce the genomic organization of Mycobacterium leprae.; Molecular microbiology. 1993. DOI : 10.1111/j.1365-2958.1993.tb01111.x.
N. Honore; S. T. Cole : Molecular basis of rifampin resistance in Mycobacterium leprae.; Antimicrobial agents and chemotherapy. 1993.
B. Heym; Y. Zhang; S. Poulet; D. Young; S. T. Cole : Characterization of the katG gene encoding a catalase-peroxidase required for the isoniazid susceptibility of Mycobacterium tuberculosis.; Journal of bacteriology. 1993.
N. Honoré; E. Perrani; A. Telenti; J. Grosset; S. T. Cole : A simple and rapid technique for the detection of rifampin resistance in Mycobacterium leprae; International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association. 1993.

1992

W. Philipp; N. Honoré; M. Sapp; S. T. Cole; R. E. Streeck : Human papillomavirus type 42: new sequences, conserved genome organization.; Virology. 1992. DOI : 10.1016/0042-6822(92)90091-3.
B. Canard; T. Garnier; B. Lafay; R. Christen; S. T. Cole : Phylogenetic analysis of the pathogenic anaerobe Clostridium perfringens using the 16S rRNA nucleotide sequence; International journal of systematic bacteriology. 1992. DOI : 10.1099/00207713-42-2-312.
B. Canard; B. Saint-Joanis; S. T. Cole : Genomic diversity and organization of virulence genes in the pathogenic anaerobe Clostridium perfringens; Molecular microbiology. 1992. DOI : 10.1111/j.1365-2958.1992.tb00862.x.
B. Heym; S. T. Cole : Isolation and characterization of isoniazid-resistant mutants of Mycobacterium smegmatis and M. aurum; Research in microbiology. 1992. DOI : 10.1016/0923-2508(92)90067-X.

1991

J. I. Rood; S. T. Cole : Molecular genetics and pathogenesis of Clostridium perfringens; Microbiological reviews. 1991.
J. Tommassen; K. Eiglmeier; S. T. Cole; P. Overduin; T. J. Larson et al. : Characterization of two genes, glpQ and ugpQ, encoding glycerophosphoryl diester phosphodiesterases of Escherichia coli; Molecular & general genetics : MGG. 1991. DOI : 10.1007/BF00273621.
K. Eiglmeier; N. Honoré; S. T. Cole : Towards the integration of foreign DNA into the chromosome of Mycobacterium leprae.; Research in microbiology. 1991. DOI : 10.1016/0923-2508(91)90074-K.
T. Garnier; B. Canard; S. T. Cole : Cloning, mapping, and molecular characterization of the rRNA operons of Clostridium perfringens; Journal of bacteriology. 1991. DOI : 10.1128/jb.173.17.5431-5438.1991.

1990

B. Canard; S. T. Cole : Lysogenic phages of Clostridium perfringens: mapping of the chromosomal attachment sites; FEMS microbiology letters. 1990. DOI : 10.1111/j.1574-6968.1990.tb04020.x.
S. Iuchi; S. T. Cole; E. C. Lin : Multiple regulatory elements for the glpA operon encoding anaerobic glycerol-3-phosphate dehydrogenase and the glpD operon encoding aerobic glycerol-3-phosphate dehydrogenase in Escherichia coli: further characterization of respiratory control.; Journal of bacteriology. 1990. DOI : 10.1128/jb.172.1.179-184.1990.
N. Honoré; S. T. Cole : Nucleotide sequence of the aroP gene encoding the general aromatic amino acid transport protein of Escherichia coli K-12: homology with yeast transport proteins; Nucleic acids research. 1990. DOI : 10.1093/nar/18.3.653.
S. A. Woods; S. T. Cole : A family of dispersed repeats in Mycobacterium leprae; Molecular microbiology. 1990. DOI : 10.1111/j.1365-2958.1990.tb00552.x.

1989

S. T. Cole : A breath of fresh air--respiratory control demystified.; Research in microbiology. 1989.
S. T. Cole; N. Honoré : Transcription of the sulA-ompA region of Escherichia coli during the SOS response and the role of an antisense RNA molecule; Molecular microbiology. 1989. DOI : 10.1111/j.1365-2958.1989.tb00220.x.
K. Eiglmeier; N. Honoré; S. Iuchi; E. C. Lin; S. T. Cole : Molecular genetic analysis of FNR-dependent promoters; Molecular microbiology. 1989. DOI : 10.1111/j.1365-2958.1989.tb00236.x.
N. Honoré; M. H. Nicolas; S. T. Cole : Regulation of enterobacterial cephalosporinase production: the role of a membrane-bound sensory transducer; Molecular microbiology. 1989. DOI : 10.1111/j.1365-2958.1989.tb00262.x.
B. Canard; S. T. Cole : Genome organization of the anaerobic pathogen Clostridium perfringens; Proceedings of the National Academy of Sciences of the United States of America. 1989. DOI : 10.1073/pnas.86.17.6676.
X. Nassif; N. Honoré; T. Vasselon; S. T. Cole; P. J. Sansonetti : Positive control of colanic acid synthesis in Escherichia coli by rmpA and rmpB, two virulence-plasmid genes of Klebsiella pneumoniae; Molecular microbiology. 1989. DOI : 10.1111/j.1365-2958.1989.tb00116.x.
B. Saint-Joanis; T. Garnier; S. T. Cole : Gene cloning shows the alpha-toxin of Clostridium perfringens to contain both sphingomyelinase and lecithinase activities; Molecular & general genetics : MGG. 1989. DOI : 10.1007/BF00259619.
S. A. Woods; S. T. Cole : A rapid method for the detection of potentially viable Mycobacterium leprae in human biopsies: a novel application of PCR; FEMS microbiology letters. 1989. DOI : 10.1111/j.1574-6968.1989.tb03678.x.
M. H. Nicolas; V. Jarlier; N. Honore; A. Philippon; S. T. Cole : Molecular characterization of the gene encoding SHV-3 beta-lactamase responsible for transferable cefotaxime resistance in clinical isolates of Klebsiella pneumoniae.; Antimicrobial agents and chemotherapy. 1989. DOI : 10.1128/AAC.33.12.2096.

1988

T. Garnier; S. T. Cole : Complete nucleotide sequence and genetic organization of the bacteriocinogenic plasmid, pIP404, from Clostridium perfringens; Plasmid. 1988. DOI : 10.1016/0147-619X(88)90052-2.
T. Garnier; S. T. Cole : Identification and molecular genetic analysis of replication functions of the bacteriocinogenic plasmid pIP404 from Clostridium perfringens; Plasmid. 1988. DOI : 10.1016/0147-619X(88)90053-4.
S. T. Cole; K. Eiglmeier; S. Ahmed; N. Honore; L. Elmes et al. : Nucleotide sequence and gene-polypeptide relationships of the glpABC operon encoding the anaerobic sn-glycerol-3-phosphate dehydrogenase of Escherichia coli K-12.; Journal of bacteriology. 1988. DOI : 10.1128/jb.170.6.2448-2456.1988.
T. Garnier; S. T. Cole : Studies of UV-inducible promoters from Clostridium perfringens in vivo and in vitro; Molecular microbiology. 1988. DOI : 10.1111/j.1365-2958.1988.tb00069.x.
P. T. Bilous; S. T. Cole; W. F. Anderson; J. H. Weiner : Nucleotide sequence of the dmsABC operon encoding the anaerobic dimethylsulphoxide reductase of Escherichia coli; Molecular microbiology. 1988. DOI : 10.1111/j.1365-2958.1988.tb00090.x.

1987

R. Freudl; G. Braun; N. Honoré; S. T. Cole : Evolution of the enterobacterial sulA gene: a component of the SOS system encoding an inhibitor of cell division; Gene. 1987. DOI : 10.1016/0378-1119(87)90392-1.
M. H. Nicolas; N. Honore; V. Jarlier; A. Philippon; S. T. Cole : Molecular genetic analysis of cephalosporinase production and its role in beta-lactam resistance in clinical isolates of Enterobacter cloacae.; Antimicrobial agents and chemotherapy. 1987. DOI : 10.1128/AAC.31.2.295.
S. T. Cole; O. Danos : Nucleotide sequence and comparative analysis of the human papillomavirus type 18 genome. Phylogeny of papillomaviruses and repeated structure of the E6 and E7 gene products.; Journal of molecular biology. 1987. DOI : 10.1016/0022-2836(87)90343-3.
R. Lidereau; S. T. Cole; C. J. Larsen; D. Mathieu-Mahul : A single point mutation responsible for c-mos polymorphism in cancer patients.; Oncogene. 1987.
A. P. Pugsley; S. T. Cole : An unmodified form of the ColE2 lysis protein, an envelope lipoprotein, retains reduced ability to promote colicin E2 release and lysis of producing cells; Journal of general microbiology. 1987. DOI : 10.1099/00221287-133-9-2411.
S. T. Cole : Nucleotide sequence and comparative analysis of the frd operon encoding the fumarate reductase of Proteus vulgaris: Extensive sequence divergence of the membrane anchors and absence of an frd-linked ampC cephalosporinase gene; European journal of biochemistry / FEBS. 1987. DOI : 10.1111/j.1432-1033.1987.tb13362.x.
T. Garnier; W. Saurin; S. T. Cole : Molecular characterization of the resolvase gene, res, carried by a multicopy plasmid from Clostridium perfringens: common evolutionary origin for prokaryotic site-specific recombinases; Molecular microbiology. 1987. DOI : 10.1111/j.1365-2958.1987.tb01944.x.
K. Eiglmeier; W. Boos; S. T. Cole : Nucleotide sequence and transcriptional startpoint of the glpT gene of Escherichia coli: extensive sequence homology of the glycerol-3-phosphate transport protein with components of the hexose-6-phosphate transport system; Molecular microbiology. 1987. DOI : 10.1111/j.1365-2958.1987.tb01931.x.

1986

S. T. Cole; M. H. Nicolas : Beta-lactam resistance mechanisms in gram-negative bacteria; Microbiological sciences. 1986.
S. T. Cole; O. Raibaud : The nucleotide sequence of the malT gene encoding the positive regulator of the Escherichia coli maltose regulon; Gene. 1986. DOI : 10.1016/0378-1119(86)90297-0.
J. H. Weiner; R. Cammack; S. T. Cole; C. Condon; N. Honoré et al. : A mutant of Escherichia coli fumarate reductase decoupled from electron transport; Proceedings of the National Academy of Sciences of the United States of America. 1986. DOI : 10.1073/pnas.83.7.2056.
S. T. Cole; R. E. Streeck : Genome organization and nucleotide sequence of human papillomavirus type 33, which is associated with cervical cancer.; Journal of virology. 1986.
A. P. Pugsley; S. T. Cole : beta-Galactosidase and alkaline phosphatase do not become extracellular when fused to the amino-terminal part of colicin N; Journal of general microbiology. 1986. DOI : 10.1099/00221287-132-8-2297.
T. Garnier; S. T. Cole : Characterization of a bacteriocinogenic plasmid from Clostridium perfringens and molecular genetic analysis of the bacteriocin-encoding gene.; Journal of bacteriology. 1986. DOI : 10.1128/jb.168.3.1189-1196.1986.
N. Honoré; M. H. Nicolas; S. T. Cole : Inducible cephalosporinase production in clinical isolates of Enterobacter cloacae is controlled by a regulatory gene that has been deleted from Escherichia coli.; The EMBO journal. 1986.

1985

S. T. Cole; C. Condon; B. D. Lemire; J. H. Weiner : Molecular biology, biochemistry and bioenergetics of fumarate reductase, a complex membrane-bound iron-sulfur flavoenzyme of Escherichia coli; Biochimica et biophysica acta. 1985.
S. T. Cole; B. Saint-Joanis; A. P. Pugsley : Molecular characterisation of the colicin E2 operon and identification of its products; Molecular & general genetics : MGG. 1985. DOI : 10.1007/BF00332940.

1984

G. Braun; S. T. Cole : DNA sequence analysis of the Serratia marcescens ompA gene: implications for the organisation of an enterobacterial outer membrane protein; Molecular & general genetics : MGG. 1984. DOI : 10.1007/BF00332766.
S. T. Cole : Molecular and genetic aspects of the fumarate reductase of Escherichia coli; Biochemical Society transactions. 1984. DOI : 10.1042/bst0120237.

1983

S. T. Cole : Characterisation of the promoter for the LexA regulated sulA gene of Escherichia coli; Molecular & general genetics : MGG. 1983. DOI : 10.1007/BF00325901.
S. T. Cole; U. Chen-Schmeisser; I. Hindennach; U. Henning : Apparent bacteriophage-binding region of an Escherichia coli K-12 outer membrane protein.; Journal of bacteriology. 1983.
R. Freudl; S. T. Cole : Cloning and molecular characterization of the ompA gene from Salmonella typhimurium; European journal of biochemistry / FEBS. 1983. DOI : 10.1111/j.1432-1033.1983.tb07594.x.
U. Henning; S. T. Cole; E. Bremer; I. Hindennach; H. Schaller : Gene fusions using the ompA gene coding for a major outer-membrane protein of Escherichia coli K12; European journal of biochemistry / FEBS. 1983. DOI : 10.1111/j.1432-1033.1983.tb07732.x.
G. Braun; S. T. Cole : Molecular characterization of the gene coding for major outer membrane protein OmpA from Enterobacter aerogenes; European journal of biochemistry / FEBS. 1983. DOI : 10.1111/j.1432-1033.1983.tb07853.x.

1982

S. T. Cole; E. Bremer; I. Hindennach; U. Henning : Characterisation of the promoters for the ompA gene which encodes a major outer membrane protein of Escherichia coli; Molecular & general genetics : MGG. 1982. DOI : 10.1007/BF00330051.
S. T. Cole; I. Sonntag; U. Henning : Cloning and expression in Escherichia coli K-12 of the genes for major outer membrane protein OmpA from Shigella dysenteriae, Enterobacter aerogenes, and Serratia marcescens.; Journal of bacteriology. 1982.
E. Bremer; S. T. Cole; I. Hindennach; U. Henning; E. Beck et al. : Export of a protein into the outer membrane of Escherichia coli K12: Stable incorporation of the OmpA protein requires less than 193 amino-terminal amino-acid residues; European journal of biochemistry / FEBS. 1982. DOI : 10.1111/j.1432-1033.1982.tb05870.x.
S. T. Cole : Nucleotide sequence coding for the flavoprotein subunit of the fumarate reductase of Escherichia coli; European journal of biochemistry / FEBS. 1982. DOI : 10.1111/j.1432-1033.1982.tb06462.x.
S. T. Cole; G. Braun; I. Sonntag; U. Henning : Expression in Escherichia coli K12 of the cloned genes for a major outer membrane protein (OmpA protein) from Shigella dysenteriae, Enterobacter aerogenes and Serratia marcescens.; Annales de microbiologie. 1982.
G. Braun; S. T. Cole : The nucleotide sequence coding for major outer membrane protein OmpA of Shigella dysenteriae; Nucleic acids research. 1982. DOI : 10.1093/nar/10.7.2367.
S. T. Cole; T. Grundström; B. Jaurin; J. J. Robinson; J. H. Weiner : Location and nucleotide sequence of frdB, the gene coding for the iron-sulphur protein subunit of the fumarate reductase of Escherichia coli; European journal of biochemistry / FEBS. 1982. DOI : 10.1111/j.1432-1033.1982.tb06768.x.
S. T. Cole; J. R. Guest : Molecular genetic aspects of the succinate: fumarate oxidoreductases of Escherichia coli; Biochemical Society transactions. 1982. DOI : 10.1042/bst0100473.

1981

J. R. Guest; S. T. Cole; K. Jeyaseelan : Organization and expression of the pyruvate dehydrogenase complex genes of Escherichia coli K12; Journal of general microbiology. 1981. DOI : 10.1099/00221287-127-1-65.

1980

S. T. Cole; J. R. Guest : Genetic and physical characterization of lambda transducing phages (lambda frdA) containing the fumarate reductase gene of Escherichia coli K12; Molecular & general genetics : MGG. 1980. DOI : 10.1007/BF00270492.
S. T. Cole; J. R. Guest : Amplification of fumarate reductase synthesis with lambdafrdA transducing phages and orientation of frdA gene expression; Molecular & general genetics : MGG. 1980. DOI : 10.1007/BF00425468.

1979

S. T. Cole; J. R. Guest : Production of a soluble form of fumarate reductase by multiple gene duplication in Escherichia coli K12; European journal of biochemistry / FEBS. 1979. DOI : 10.1111/j.1432-1033.1979.tb06263.x.